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23rd April 2018, 11:02 AM
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Re: Osmania University M.Sc Zoology Syllabus

Can you provide me the syllabus of Two Year M.Sc. (Zoology) Programme offered by Department of Zoology, Osmania University?
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23rd April 2018, 11:04 AM
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Re: Osmania University M.Sc Zoology Syllabus

The syllabus of Two Year M.Sc. (Zoology) Programme offered by Department of Zoology, Osmania University is as follows:

M.Sc. Zoology
Semester I
CORE PAPER

Paper 1

Structural Biology [SB]

UNIT IBasic concepts of Biomolecules and Structural Biology
1.1 Biomolecules and their significance carbohydrates, proteins, amino acids, nucleic acids and lipids.
1.2 Chemistry and structure of mono, oligo and polysaccharides. Deoxysugars, aminosugars and glycosides
1.3 Classification and structures of proteins primary, secondary, tertiary and quaternary.
1.4 Classification, structure and function of lipids, fatty acids, triglycerides; phospholipds, cerebrosides, steroids
1.5 Nucleic acids Structure of DNA and RNA , DNA polymorphism, RNA types.

UNIT IIEnzymes and Metabolism
3.1 Classification, nomenclature and properties of enzymes catalysis and energy of activation; Enzyme kinetics, MichaelisMenten Constant; (Km values) and LB plot; mechanism of enzyme action and regulation of enzyme activity
3.2 Metabolism of carbohydrates Glcolysis; TCA cycle; Gluconeogenesis; biological oxidation; role of respiratory chain in energy capture; ATP synthesis
3.3 Catabolism of amino acids Transamination, deamination and decarboxylation
3.4 Oxidation and biosynthesis of fatty acids
3.5 Metabolic disorders of different biomolecules (carbohydrates, proteins, lipids)

UNIT IIICellular Organization
2.1 Molecular organization and functions of cell membranes
2.2 Cell permeability Transport across the cell membrane; transport of small molecules; Carrier proteins; Ion pumps; membrane bound enzymes
2.3 Cell communications Inter cellular communication and gap junctions; chemical signalling between the cells; strategies of chemical signaling
2.4 Signaling mediated by intracellular receptors; signaling mediated cell surface receptors second and third messengers; CAMP, Gproteins, Ca++, Inositol Triphosphate (IP3) and prostaglandins
2.5 Cell cycle; molecular events in cell cycle; mitotic spindle

UNIT IV - Functional Biology of Nucleic Acids
4.1 DNA replication semi conservative, enzymology of DNA replication, replication of circular DNA, initiation, elongation and termination of replication process. Proof reading function of DNA polymerases
4.2 Enzymatic synthesis of RNA.
4.3 Protein synthesis Events of protein synthesis; transcription in prokaryotes and eukaryotes; post transcriptional processing.
4.4 Regulation of genetic code Wobbles concept, translation in prokaryotes and eukaryotes.
4.5 DNA repair mechanism High fidelity of DNA sequence Repair of damage caused by UV light, Eukaryotes repair systems.

PRACTICAL
1 Determination of proteins by Biuret method/ Folin Phenol method
2 Determination of glucose by Somogi / Anthrone method
3 Determination of lipids by Vanlin method
4 Determination of glycogen by Kemps method
5 Estimation of cholesterol
6 Determination of enzyme activities of SDH and LDH
7 Effect of substrate concentration and pH on SDH activity
8 Protein fractionation using sodium sulphate
9 Estimation of DNA and RNA
10 Electrophoretic analysis of proteins/DNA
11 Feulgen reaction method for DNA localization.
12 Submission of assignment on structure of Biomolecules, mechanism of enzyme action ,
Metabolic cycles, DNA, RNA, protein synthesis [To be submitted at the time of
Examination 10 Marks]

Suggested Books
1 Textbook of Biochemistry by Harper
2 Textbook of Biochemistry by Lehninger
3 Textbook of Biochemistry by Stryer and Stryer
4 Textbook of Biochemistry by Conn and Stumpf
5 Textbook of Biochemistry by A.B.V. Rama Rao
6 Cell and molecular biology by De Robertis and De Robertis, 8th ed.
7 Molecular Biology by Friefielder
8 Molecular cell biology by Darnell, Lodish and Baltimore (Scientific American Books)
9 Molecular biology by H. D. Kumar
10 Biochemistry and molecular biology by W. H. Elliot and D. C.Elliot(OU Press)
11 Molecular Biology of Cell by Bruce Alberts et al
12 Cell by Karp

Syllabus Committee
1 Prof. P. Nagaraja Rao
2 Dr. Rafath Yasmeen
3 Dr. B. Jyothi
4 Dr. S. Padmaja


Syllabus M.Sc. (Zoology) Programme Department of Zoology, Osmania University






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