Msc Biotechnology Syllabus Mumbai University

My sister has completed B.SC Biotechnology Course in last year and this year she wants to take admission in PG Degree at Mumbai University. So she wants to see syllabus of M.SC Biotechnology Course before taking admission. So will you give link to download syllabus of M.SC Biotechnology Course?

[pawan]

As you are looking for syllabus of M.SC Biotechnology Course of Mumbai University, so here I am giving detailed syllabus:

Mumbai University M.SC Biotechnology Syllabus
Semester- I
Biochemistry

Unit I
Proteins :
Primary structure of proteins and their determination – end group
analysis; cleavage of disulphide bond; separation, purification,
characterization of polypeptide chain; specific peptide cleavage
reactions.
Secondary structure – Ramachandran plot, helical structure, beta
structure; Tertiary structure- fibrous (Collagen) and globular (Myoglobin)
structure. Protein stability, protein denaturation.
Quaternary structure – (Haemoglobin) subunit interaction,
symmetry, subunit composition determination

Unit II
Signal transduction
Cell signalling pathways that control gene activity- TGF-Beta and
activation of Smads: Regulation of TGF-Beta by negative feedback
loops. Cancer and loss of TGF-Beta signalling,

Unit III
Lipids
Lipoproteins – structure, function, disorders and dysfunction in Alzheimer’s disease.

Unit IV
Neurochemistry
Anatomy and functions of neuron, organization of brain, neuronal
pathways and systems, propagation of nerve impulse, ion conducting
channels, synapses and gap junction, neurotransmitters, neurotoxins

Immunochemistry
Unit I
Immunoglobulins
Hematopoiesis, Immunoglobulin fine structure, Immunoglobulin
superfamily ,Multigene organization of Ig gene, Variable region gene
rearrangement, Generation of antibody diversity, Class switching
among constant region. Synthesis, assembly, and secretion of
immunoglobulins

Unit II
Complement system
Activation, Regulation, Biological consequence of complement
activation, Complement deficiency

Unit III
MHC and Regulation of immune response
Cellular distribution of MHC molecule, Antigen processing and
presentation – exogenous and endogenous antigen processing. Self -
MHC restriction of T cells. Presentation of non-peptide antigens.
Activation of B and T lymphocytes, T-cell regulation.

Unit IV
Cytokines
Properties, receptors, antagonists, diseases, therapeutic use of cytokines

Genomes and Transcriptomes
Unit I
Gene evolution and The human genome
Human genome project, the content of human nuclear genome,
tandemly repeated DNA, interspersed genome-wide repeats.
Human mitochondrial genome.
Genome evolution-Acquisition of New Genes (gene duplication,
from other species, transposable elements), Non-coding DNA

Unit II
Mapping Genomes
Genetic Mapping: DNA markers for genetic mapping, Physical
Mapping: Restriction Mapping, Fluorescent in situ hybridization
(FISH), Sequence tagged site (STS) mapping.

Unit III
Transcription Initiation in prokaryotes and eukaryotes
DNA-Protein interactions during Transcription Initiation,
Regulation of Transcription initiation.

Unit IV
Synthesis and Processing of RNA
Synthesis of eukaryotic mRNAs by RNA polymerase II, Intron
splicing.
Synthesis and processing of Non-coding RNAs: Transcript
elongation and termination by RNA polymerases I and III, Introns
in eukaryotic pre-rRNA and pre-tRNA.
Processing of Pre-RNA.
Degradation of mRNAs

Biophysics
Unit I
DNA Topology
Different forms of DNA, - A/B/C/Z and RL form of double helical
DNA, Triple Helix, Nucleic acid binding protein – Leucine Zipper,
Zinc fingers, OB fold, Beta Barrel, Helix-turn-helix, Helix-loophelix.
Linking number, Supercoiling, Topoisomerases.

Unit II
Protein secondary structure
Protein folding. The different pathways of protein folding and its
co-relation with protein stability. Molecular chaperons

Unit III Advances in Microscopy
Different versions of electron microscopy, Confocal Microscopy

Unit IV
Membrane mimicry
Liposome structure and their uses in drug targeting. solubilisation
of the membrane by using different detergents. Membrane mimicry.