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Old 19th August 2014, 08:27 AM
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Default Re: Department of Zoology Bharathiar University

The syllabus of M. Tech., Molecular Biology and Human Genetics (CBCS pattern) of Department of Zoology Bharathiar University is as follows:

M. Tech., Molecular Biology and Human Genetics (CBCS pattern) with Compulsory Diploma in Biomedical Instrumentation

Eligibility Condition:
B.Sc. Zoology
B.Sc. Advanced Zoology
B.Sc. Applied Zoology
B.Sc. Life Sciences
B.Sc. Animal Science and Biotechnology
B.Sc. Advanced Zoology and Biotechnology

CELLULAR AND MOLECULAR BIOLOGY
Unit – I
Structure and organization of cell – Bacteria and Virus – Differences between Prokaryotic and Eukaryotic cells, Structure, Composition and Function of Plasma membrane, Mitochondria, Endoplasmic reticulum, Golgi complex, Vacuoles, Ribosomes, Mircosomes, Cytoskeleton and Peroxisomes, Chemical composition and function of Nucleus, Nucleolus and Chromosomes.

Unit – II
Overview of Cell cycle – mitosis – meiosis – Factors modifying the cell cycle – genes regulating the cell cycle - microtubules – motile functions of microtubules – microfilaments – microfilament based cell motility – nucleus and its molecular constituents – organization of chromatin and cell nucleus

Unit III
Membrane Biogenesis – Lipid biogenesis and membrane asymmetry – membrane models – active transport – passive transport – cell signaling – cell adhesion – cell junctions – cellular oxidations and mitochondria – photosynthesis and chloroplast – chloroplast transport
Unit IV
Development of motile male gametes – development of female gametes – fertilization in animals – game to genesis and gertilization in higher plants
Unit V
Characteristics of Cancer – establishing the genetic basis of cancer – viruses and cancer –
Multi step progression from initiation to malignancy – the role of chemicals and radiation in multi step progression

Reference:
1. G. Karp. 1979. Cell Biology, Mc Gra Hill Kogatusha Ltd. Japan.
2. De Robertis E.D.D and De Robertis E.M.F. 1980. Cell and Molecular Biology. Holt –
Sunders international (Edn.)
3. C.J. Avers. 1976. Cell Biology. D. Van Nostrand Co., New York.
4. J.D. Watson. 1977. Molecular Biology of the gene 3rd (Edn.) W.A.Benjamine Inc. London.
5. A.L. Lehninger. 1984. Principles of Biochemistry. CBS Publishers and Distributors,
New Delhi.

Practical:
1. Mendelian genetics calculations
2. Identification of different stages of meiosis and mitosis (slides).
3. Identification of sex chromatin in buccal smear test.
4. Preparation of mitosis in Onion root tip.
5. Squash preparation in Grasshopper testis.

HUMAN GENETICS
UNIT-I
History of Human Chromosome Research - Denver Conference (1940) - Chicago Conference
(1966) - Paris Conference (1971) - Nomenclature of Human Chromosome.

UNIT-II
Identification of Human diploid chromosome - peripheral blood cultures - banding techniques -
G-band; Q-band; C-band; R-band - Identification of 23 pairs of Human chromosomes by band
position.

UNIT-III
Chromosomal syndromes: Autosomal syndromes - Sex chromosomal syndromes - Structural
chromosomal syndromes.

UNIT-IV
Prenatal diagnosis: Chorionic villi sampling - Foetoscopy, Ultrascopy - Amniocentesis. b)
Postnatal diagnosis: Peripheral blood leucocyte culture - Sister Chromatid Exchange - Fragile
site - Mitotic index. c) Genetic Counseling.

UNIT-V
Hereditary forms of Cancer - Oncogenes and Cancer - Chromosomes and Cancer - Cancer and the
environment.

Reference Books:
1. Human Heredity Principles and issues -- by Michael R. Cumming's. 3rd Edition.
2. Genetics Medicine - by Karl. H. Muench Elsevier Pb. London
3. Human Genetics by Elof Axel Carlson, TATA Mc Graw-Hill Pb. New Delhi.

Practicals:
1. Problems related to Mendelian laws.
2. Pedigree analysis
3. Peripheral blood leukocyte culture for chromosomal studies
4.Mitotic indices
5. Sister chromatid exchange -determination
6. Micronucleus test
7.Chromosomal disorders-Numerical, Structural

BIOINFORMATICS AND GENOMICS
Unit I
Biology of cells-Biology of Environment-Cell Energetics and Respiration- Calculus-Integration.

Unit II
Internet and Intranet-Application of IT-Database Management Systems and
telecommunications.-Searches on MEDLINE, CD-ROM

Unit III
Chemical Bonding and Atomic and Molecular Orbital-X-ray crystallography of bio molecules –
Molecular mechanics and molecular dynamics of Protein, Pesticides, Nucleotides.

Unit IV
Concept of molecular modeling-Genome data bank-microbial and cellular data banks
Analysis tools for sequence data banks.

Unit V
Introduction to Genomics- biological data modeling-Genomic mapping and single nucleotide
polymorphisms-Micro array gene expression analysis –Genomics databases.

References
1.Jurnak, F.A. and Mc Pherson, A. 1985. Biological Macromolecules and Assembilies., New
Delhi
2.T.K. Manicavachagom Pillai – Calculas
3.Powell, HTML, The complete reference , Tata Mac – Graw Hill, 1988.
4.Winter, M. J. 1996. Chemical Bonding , Oxford University Press, Inc., New York, 91 pp.
5.Setubal J., Meidanis J. Introduction to computational molecular biology. PWS Publishing Co.,
Boston (1996)
6.Matthew F. Schlecht. Molecular modeling on the PC &. Introduction to Database systems, J.M.
Martin , Princeton – Hall.

Practical
1.Bioinformatics and the Internet
2.Protein Sequence Analysis
3.Molecular Graphics and Evaluating Protein Structure
4.Small Molecule Generation and assessment
5.Free energy calculations

ELECTIVE PAPER –I 08ZOOC1EA
IMMUNOTECHNOLOGY
Unit-I.
Introduction to Immune system; cellular and humoral immunity; complement; molecular basis of
Immune diversity. Host-parasite interaction; Immunity and infection: immunity to bacteria,
virus, protozoa, fungi and tumor.

Unit-II.
Antigens and antigenicity. Polyclonal and monoclonal antibody production and purification.
Conjugation of antibody with enzymes, fluorochrome and toxin. Humoral immune response and
cell mediated immune response.

Unit-III.
Immunity to infections. Immunological techniques: RIA, ELISA, Immunocytochemistry,
immunofluorescence, Immunoblotting,

Unit-IV.
Flurescence antibody techniques, flow cytometry, Fluorescence in situ hybridization.
Immunopathology and immunological disorders.

Unit-V.
Principles and methods of vaccine preparation – Edible vaccines. Antibody engineering and
structure. Cytokines and immunotherapy.

References
1. Immuno-Biotechnology by Surendra Naha and Ravidra Narain, Dominant distributors
and Publishers, New Delhi, 2006.
2. Immunology by Ivan Roitt, Brostoff and Male. 5th Edition. Mosby publications, London.
3. Kuby Immunolgy by Richard A. Goldsby (Editor), Barbara A. Osborne, Thomas J. Kindt,
Janis Kuby, Janis Kuby, Richard A. Goldsby. Richard A. Goldsby (Editor), Barbara A.
Osborne, Thomas J. Kindt, Janis Kuby, Janis Kuby, Richard A. Goldsby. W H Freeman
& Co. 2006
4. Cellular and Molecular Immunology by Abul K. Abbas, Andrew H. Lichtman. Elsevier
Science Health Science. 2005.

Practical
1. ELISA
2. Immuno electrophoresis

DIPLOMA IN BIOMEDICAL INSTRUMENTATION
DIPLOMA PAPER - I 08ZOOC1LA
Course Objective: To make an introduction to the modern Biomedical instruments and
systems, their features and applications

Unit I: Basic concepts of electronics
Electronic components and circuit analysis – amplifiers – filters – analog to digital and
digital to analog conversion – digital signal processing – microcomputers – display
devices – recording devices – software and programming languages

Unit II: Analysis of molecules in clinical medicine
Spectrophotometry – amperometric biosensors for oxygen and glucose – ion selective
electrodes for pH and CO2 - flame photometry – mass spectrometry - carbon dioxide
concentration measurement by Infrared transmission spectroscopy nitrogen by emission
spectrometry – drugs by flurometry and chromatography – electrophoresis – DNA
sequencing

Unit III: Cardiovascular measurement: the cardio vascular system
Measurement of blood pressure- sphygmomanometer – blood flow – cardiac output and
cardiac rate – electrocardiography – echo cardiography – ballistocardiography –
plethysmography – magnetic and ultrasonic measurement of blood flow

Unit IV: Introduction to the physiology of cardiac, nervous, muscular and
respiratory systems - transducers and electrodes
Different types of transducers and their selection for biomedical applications – electrode
theory different y types of electrodes –reference electrodes – hydrogen calomel – Ag-
AgCl –pH electrode – selection criteria of electrodes

Unit V: measurement of electrical activities
Nervous system - electromyography – electroencephalograph and their interpretation –
evoked potentials - eye, ERG, EOG

References:
1. Handbook of Biomedical Instrumentation – R.S.Khandpur, TMH Publishing
company Ltd. New Delhi
2. Introduction to Biomedical Equipment Technology – Joseph J Carr, John M
Brown, Pearson Education (Singapore) Pvt. Ltd
3. Biomedical Instrumentation and Measurements – Leslie Cromwell, Prentice Hall
of India Pvt.Ltd, New Delhi
4. Bioinstrumentation – John G.Webster, John Wiley & sons, Inc.
5. Medical Instrumentation: application and design - John G.Webster, John Wiley &
sons, Inc.
6. Biomedical Instrumentation and Measurements – Leslie Cromwell, Fred
J.Weibell, Erich A.Pfeiffer. Prentice Hall of India 2008.

BIOCHEMICAL GENETICS
UNIT-I
Introduction to Inborn errors of Metabolism-One gene One Enzyme hypothesis – Genes
involved in metabolic disorders

UNIT-II
Carbohydrate metabolic disorders: Diabetes Mellitus - Clinical features and laboratory
findings in insulin resistance - Ketosis and lactic acidosis - Galactoserria (G6PD)-
Mucopolysaccharadosis

UNIT-III
Lipid metabolic disorders: Lipidosis – atherosclerosis - Cystic fibrosis - thalassemias,
sickle cell anaemia – Hemophilia – hemoglobinopathies

UNIT-IV
Amino acid metabolism-Phenyl ketonuria- Homo Cystenuria – Alkaptonuria. Alpha-1-
antitrypsin deficiency, obesity

UNIT-V
Nucleic acid and Protein metabolism - Gout Syndrome – Lesch Nyhans syndrome –
Duchenays muscular dystrophy (DMD)– Tay sachs disease

References
1. Animal Genomics, Bhanu Chowdhary, S.kargeer AG, P.O. box 4009 Switzerland
2.The Biology Chemistry Interface, cooper and Raymond, Daya Publishing House, New
Delhi
3.Genetics The Continuity of Life, D.J. Fairbanks, Daya publishing House, New Delhi
4.concepts in biochemistry, Boyer,R. Narendra book agency, Delhi
5.Textbook of Pediatrics, S.T. Achar and J. Vishvanathan, Orient Longman Limited,
1988.
6. Williams. Textbook of Endocrinology.

Practical
1.Quantitative analysis’s of Phenyl Ketonuria ( PKU) by using urine samples.
2. Quantitative analysis of homocysteine by using urine samples.
3. Protein estimation from blood serum by Lowery et al method
4. Estimation of blood glucose level
5. Demonstration of Amniocentesis.

PROTEOMICS
Unit-1.
Introduction to proteomics. Study of multiprotein systems. Proteome. Life and death of a
protein. Proteins as modular structures. Functional protein families. Deducing proteome
from the genome. Analytical proteomics. Significance for analytical proteomics. Peptide
separations. Protein extracting from biological samples. Protein digestion techniques.
Proteases, Cyanogen bromide and In-gel digestion.

Unit-2.
One dimensional SDS-PAGE. Two dimensional SDS-PAGE. Problems with 2D-SDSPAGE.
Ionization techniques for macromolecules. Preparative IEF. High-performance
liquid chromatography. Capillary electrophoresis.

Unit-3.
Mass spectrometer analysis of proteins and peptides. MALDI-TOF MS instruments.
MALDI. TOF Mass analyzer. ESI Tandem MS instruments. Tandem Mass analyzers.
Triple Quadrupole Mass Analyzer. Ion-Trap Mass Analyzer. Q-TOF and Fourier
Transfor-Ion Cyclotron Resonance MS instruments.

Unit-4.
Protein identification by peptide Mass fingerprinting. Peptide sequence analysis and
identification by Tandem Mass spectrometry. Mining proteomics. SALSA. Protein
expression profiling. Identification of protein-protein interactions and protein complexes.
Mapping protein modifications.

Unit-5.
Protein chips. SELDI. Microsequencing. Proteomics in cancer research. Proetomic
analysis in pancreatic ductal adenocarcinoma and Human breast carcinoma. Profiling of
chemoresistant cancer cells. Proteomics in disease understanding.

References
1. Protein Biochemistry and Proteomics by Hubert Rehm. Academic Press, Elsevier.
USA. 2006.
2. Proteomics today by Mahmoud Hamdan and Pier Giorgio Righetti. John Wiley & sons.
New Jersey. USA. 2005.
3. Introduction to Proteomics by Daniel C. Liebler. Humana Press, Totowa, NJ, USA.
2002.

Practicals
1. Purification of proteins
2. SDS PAGE
3. Softwares used in proteomics

Fee Structure



Name of the Faculty Designation
Dr. K. Murugan, M Sc.,M.Phil.,Dip.Ent.,Ph.D.,D.Sc., Professor and Head
Dr. M. Ramesh M.Sc. M.Phil., Ph.D., FAZ, DIPC Associate Professor
Dr. P. Saravana Bhavan M.Sc., B.Ed, Ph.D Associate Professor
Dr. V. Ramasubramanian M.Sc., M.Phil., Ph.D. Assistant Professor
Dr. C Gunasekaran Assistant Professor
Dr. S Kannan Assistant Professor

Contact Detail:
Department of Zoology
School of Life Sciences
Bharathiar University
Coimbatore - 641 046
Tamil Nadu. India

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  #3  
Old 13th May 2015, 08:27 AM
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Default Department Of Zoology Bharathiar University

Will you give me information about the Department of Zoology of the Bharathiar University as I want t o know about the same ?
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  #4  
Old 13th May 2015, 09:33 AM
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Join Date: Apr 2013
Default Re: Department Of Zoology Bharathiar University

Department of Zoology of the Bharathiar University was started in 1973 as one of the departments of Madras University Post Graduate center.


Courses offers :

M.Sc. Animal Science

M.Sc. Animal Biotechnology

M.Sc. Human Genetics and Molecular Biology

M.Phil.

Ph.D.


Fee structure :




Fees to be paid by the candidates at the time of admission (one time payment):

Admission fee (one time) 60
Registration fee (one time) 120
Matricula fee (one time) 60.00
Recognition fee (other than BU) (one time) 390.00
Administrative Fee (one time) (Rs.50/-per year 2x50) 120
Placement Fee (One time) 600
Caution Deposit (Refundable) 1200
Library Fee (Per year) 360
Sports Fee (per year) (for all full time courses) 60
Internet & ID Card Fee (per year) 1000
Students Welfare Fund (per year) 120
Insurance (per year) 80

Total Amount for Other University Students 4170.00
Total Amount for Bharathiar University Students 3720.00


Address:
Bharathiyar University
Coimbatore, Tamil Nadu ‎

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Old 9th May 2020, 09:05 AM
Khushboo Khatri
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Default Mba books

I want mba books of bharathiar university of Thakur publications of 4th sem HR-employee training and development, labour welfare and industrial relations(legislation) ,marketing- brand management, distribution management,strategic management:Indian and
global context total 5 subjects i want plz i want full notes
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