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  #1  
26th March 2016, 10:58 AM
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Synthesis Of Proteins

Hi buddy I am an science faculty student and making project on Synthesis Of Proteins and for the same I am looking for study material , so can you arrange some material for me ??
  #2  
26th March 2016, 11:05 AM
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Join Date: May 2012
Re: Synthesis Of Proteins

As you said you are making project on Synthesis Of Proteins and for it looking for material , so for your help I am providing a pdf which having lotes of material related to same topics

Here is some content from pdf

Protein Synthesis Occurs by Initiation, Elongation, and Termination

• The ribosome has three tRNAbinding sites.

• An aminoacyltRNA enters the A site.

• PeptidyltRNA is bound in the P site.

• Deacylated tRNA exits via the E site.

• An amino acid is added to the polypeptide chain by transferring the
polypeptide from peptidyltRNA in the P site to aminoacyltRNA in the A site.

Special Mechanisms Control the Accuracy of Protein

Synthesis

• The accuracy of protein synthesis is controlled by specific mechanisms at
each stage.

Initiation in Bacteria Needs 30S Subunits and Accessory

Factors

• Initiation of protein synthesis requires separate 30S and 50S ribosome
subunits.

• Initiation factors (IF1, 2, and 3), which bind to 30S subunits, are also
required.

• A 30S subunit carrying initiation factors binds to an initiation site on mRNA
to form an initiation complex.



• IF3 must be released to allow 50S subunits to join the 30SmRNA complex.

A Special Initiator tRNA Starts the Polypeptide Chain

• Protein synthesis starts with a methionine amino acid usually coded by
AUG.

• Different methionine tRNAs are involved in initiation and

elongation.

• The initiator tRNA has unique structural features that distinguish it from all
other tRNAs.


• The NH2 group of the methionine bound to bacterial initiator tRNA is
formylated.


Synthesis Of Proteins study material
Attached Files
File Type: pdf Synthesis Of Proteins study material.pdf (9.78 MB, 193 views)


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