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19th August 2014, 04:12 PM
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Re: Syllabus of M.Sc Bioinformatics Entrance exam of Jamia Millia Islamia

As you want to get the syllabus of M.Sc Bioinformatics Entrance exam of Jamia Millia Islamia so here it is for you:

Some content of the file has been given here:

Animal Diversity – I (BSB)

Unit I: Introduction to Invertebrate
General Principles of Taxonomy and Animal classification. Salient feature, and
classification upto order in nonchordates.

Unit II: Phylum-Protozoa Porifera and Coelentrata
General characters of Protozoa: Type study of Paramecium caudatum. Protozoa and Human
diseases. Origin of Metazoa, metamerism and symmetry. Type study of Sycon, with reference
to reproduction and development. Polymorphism, Corals and Coral reef.

Unit III: Phylum-Platyhelminthes and Nematohelmithes, Annelida
General characters Study of Taenia, Parasitic adaptations. Type study of Ascaris lumbriocodies. Types
and significance of Coelom, Study of Nephridial system in annelids.

Unit IV: Phylum Arthropoda
General characters: Metamorphosis in insects. Economic importance of insects. Lac culture,
Sericulture, Apiculture and Prawn culture, Social insects and their life cycle. Type Study of
Palaemon.

Unit V: Phylum Mollusca, Echinodermata and Minor Phyla
General characters: Type Study of Pila globosa. Torsion and detorsion in gastropods General
Characteristics, Life history and development of asterias (star fish). General introduction of
minor phyla and its example.

Recommended Books

1- Ganguli, B.B., Sinha, A.K. and Adhikari, S., 2001, Biology of Animals, (Vol. I and
III), New Central Book Agency, Calcutta.
2- Kotpal, R.L., 1990, Modern Text Book of Zoology, Invertebrates, 8th
Edition, Rastogi
Publication, Meerut.
3- Jordan, E.L., P.S. Varma, 2001, Invertebrate Zoology, S. Chand & Co., New Delhi.

Plant Diversity – I (BSB)

Unit I: Cyanobacteria
General features, Taxonomic position, Distribution, Cell structure, Heterocyst, Water bloom,
Reproduction and economic importance with special reference to Nostoc.

Unit II: Algae
General features, Classification, Distribution, Range of thallus organization, Reproduction,
Economic importance with special reference to Chlamydomonas, Volvox, Oedogonium,
Chara, Ectocarpus, Vaucheria and Polysiphonia.

Unit III: Fungi
General features, Classification, Range of thallus organization, Reproduction, Parasexual
cycle and economic importance with special reference to slime molds, Albugo, Phytophthora,
Penicillium, Agaricus, Puccinia and Alternaria.

Unit IV: Lichens
General features, Classification, Distribution, Thallus structure, Ecological significance and economic importance.

Unit V: Bryophytes
General features, Classification, Distribution, Thallus organization, Reproduction, Economic
importance with special reference to Riccia, Marchantia, Anthoceros and Funaria.

Unit VI: Pteridophytes
General features, Classification, Structure, Reproduction, Alternation of Generation, Stelar
evolution, Heterospory and seed habit. Type study: Psilotum, Lycopodium, Selaginella,
Equisetum and Pteridium.

Recommended Books
1- Alexopoulus, C.J., Mims, C.W. and Blackwell, M., 1996, Introductory Mycology, John Wley and Sons, Inc.
2- Kumar, H.D., 1988, Introductory Phycology, Affiliated East-West press Ltd., New Delhi.
3- Parihar, N.S., 1991, Bryophyta, Central Book Depot, Allahabad.
4- Parihar, N.S., 1996, Biology & Morphology of Pteriodophytes, Central Book Depot, Allahabad.
5- Stewart, W.N. and Rathwell, G.W., 1993, Paleobotany and the Evolution of Plants, Cambridge University Press.
6- Vashishta, P.C., 1991, Pteridophyta (Vascular Cryptogam), S. Chand & Co. Ltd. Delhi.
7- Pandey, Mishra & Trivedi, 2001, A Text Book of Botany, Vol. I & II, Publishing House, New Delhi.

Cell Biology (BSB)
Unit I
Cell as a basic unit of living system. Biochemical composition of cell : protein, lipid, carbohydrate, nucleic acid. The cell theory. Ultrastrcuture of cell.
Membrane composition, Early studies on Plasma Membrane. The lipid bilayer/membrane. A summary of membrane functions – simple diffusion, Facilitated transports. Active transport, Endocytosis, Pinocytosis, Phagocytosis, Exocytosis.

Unit II
Structure and Function of the Endoplasmic reticulum, Golgi complex, Lysosome, Ribosome, Mitochondria and Chloroplast. Brief introduction to photosynthetic process. Evolution of mitochondria and chloroplast.

Unit III
Structure and Function of Nucleus, Nuclear envelope, Structure of Chromatin, Nucleosome and chromosome, Cell cycle, Mitosis & Meiosis.

Unit IV
Cell-cell interaction, Cell locomotion (amoeboid, flagellar and ciliar). Muscle and Nerve cell, Cell senescence and death, Cell differentiation.

Unit V
Nucleic acids, Structure of DNA, DNA as genetic material: discovery of transformation & experiment of Hershey & Chase, DNA replication, Structure and types of RNA, transcription, Post transcriptional modifications, Methylation, Capping & splicing, Polyadenylation.

Unit VI
Genetic Code: Evidence & Essentiality of Codon, Triplet code, start and stop condons. Overlapping genes and reading frames, universality of genetic code, Protein synthesis, mechanism in prokaryotes and eukaryotes, Post translational modification and cell secretion.

Recommended Books
1- Robertis De, E.D.P. & E.M.F.De Robertis, 1987, Cell and Molecular Biology, Lea & Febiger.
2- Bruce Albert, Dannis Bray, Julian Lewis, Martin Raff. Keith Roberts, James D. Watson, 2000, Molecular Biology of Cell, 4th Edition, Garland Publishing Inc., New York, USA.
3- Harvey Lodish, 1999, Molecular Cell Biology, W.H. Freeman & Co. 4th Ed.
4- Darnell, J.E., 2000, Molecular Cell Biology, W.H. Freeman & Co.

Organic Chemistry-I (BSB)
Unit I : Structure and Properties
Electronic configuration, Atomic and Molecular orbitals, Convalent bond, Hybrid orbitals: sp, sp2 & sp3, Bond length, Bond angle and Bond dissociation energy, Polarity of bonds and molecules, Intermolecular forces, Melting point, Boiling point, Solubility, Acid & Base in organic chemistry.

Unit II : Alkanes and Radical reactions
Structure of methane, ethane, propane & butane, Nomenclature, Physical propeties, Reactions of alkanes: combustion, pyrolysis and halogenation. Radical reactions: production and reaction of radicals, homolytic bond dissociation energies, relative stabilities of raidcals, halogenation of methane, halogenation of higher alkanes, selectivity of bromine, other important radical chain reactions.

Unit III : Alkyl halides and Ionic reactions
Structure, classification, nomenclature and physical properties, Reactions, of Alkyl halides: Nuleophilic substitution reactions (Nucleophiles & leaving groups, Thermodynamics & kinetics, SNI & SN2 reactions: mechanism, kinetics, stereochemistry and reactivity, Carbocations: structures, relative stabilities & rearrangement, Factors affecting rates of SNI & SN2 reactions), Eliminaiton reactions of Alkyl halides: Dehydrohalogenation, E1 & E2 reactions and cleavage of Alkenes: Halogenation and ozonolysis.

Unit IV : Alkenes
Carbon-Carbon double bond, structure of ethylene, propylene & butylene, Geometric isometric isomerism, Nomenclature & Physical Properties, Reactions of Alkenes: Addition reactions (addition of hydrogen, hydrogen halides, sulphuric acid, water, alkenes, alkanes & radicals), preparation of alcohols, oxymercuration-demercuration and hydroboration oxidation processes, substitution reactions and cleavage of Alkene: Halogenation and ozonolysis.

Unit V : Alcohols
Structure & Nomenclature, Physical properties, Chemistry of OH group, Alcohols as acids & bases, Reactions of Alcohols: Reactions with hydrogen halide, phosphorous trihalide and thionyle chloride, Conversions of alcohols into mesylates, tosylates, alkyl halide & alkyl phosphates, Dehydration of alcohols (mechanism, carbocation stability & molcecular rearrangement), synthesis of ethers from alcohols, Intermolecular dehydration, Williamson synthesis, Oxidation of alcohols, Methods of protecting –OH group.

Unit VI : Aldyehydes and Ketones
Structure, Nomenclature and Physical properties, Nucleophilic addition to carbon-oxygen double bond, Reaction of Aldehydes and Ketones: Oxidation, Baeyer Villager oxidation, Reduction to alcohols & hydrocarbons: Clemmensen & Wolff Kishner reduction, Reductive amination, Addition of water & alcohols (hydrates, hemiacetal, hemiketal, acetal, ketal, cyclic ketals, thioacetals & tioketals), Additions of derivatives of ammonia (reactions with hydroxylamine, hydrazine, phenylhydrazine & semincarbazide), Addition of hydrogen cyanide & sodium bisulphite, Addition of Halides : Wittig reaction, Aldol reactions: enolate ions, keto-enol tautomerism, reactions via enol and enolate ions (recemization, halogenation of ketones, haloform reaction, aldol condensation & related reactions).

Unit VII : Carboxylic acids and their Derivatives
Structure, Nomenclature, Physical properties and Acidity of carboxylic acids, Reactions of carboxylic acids: Nucleophilic substitutions at acyl carbon, Conversion into acyl chloride, anhydrides, lactones, nitriles esters, amides and lactams, Reduction of carboxylic acids, substitution in alkyl or aryl group, Decarboxylation of carboxylic acids, Reactions of acyl chloride and acid anhydrides, Reaction of Esters: Conversion into acids and acids and acid derivatives (Hydrolysis, ammonolysis & alocholysis), Reduction to alcohols, Reactions with carbanion (claisen condensation).

Unit VIII : Amines and Amides
Structure, Nomenclature, Physical properties and Basicity of Amines, Reactions of Amines: Oxidation, Reactions of Amines with nitrous acid, Replacement and coupling reactions of Arenediazonium salts, Conversion to amides and sulfonamides, Hofmann and Cope eliminations. Reactions of Amides: hydrolysis, conversion to imides, Hofmann degradation.

Recommended Book
1- Morrison & Boyd, 1992, Organic Chemistry, Addiso-Wesley Pub. Co. 6th Edition.
2- Finar, I.L., 1988, Organic Chemistry, vo. I & II, Wiley John & Sons.
3- Soni, P.L., 2001, Organic Chemistry, S. Chand & Co., New Delhi.


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