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23rd August 2014, 08:37 AM
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Join Date: Apr 2013
Re: Previous paper for IISC Entrance Exam

Here I am giving you question paper for Indian Institute of Science Bangalore PHD entrance examination below :

BIOLOGICAL SCIENCES
1. Which test is commonly uscd to identify a rcducing sugar?
(A) Iodine test
(B) Benedict's tes!
iurct test (C)- B'
(D) Emulsion tcst
2. Which process does NOT occur in mitochondria?
(A) fatty acid biosynthesis
(B) protein synthesis
(C) P-oxidation
(D) DNA synthesis
3. Using si te-directed mutagcnesis, four mutants were generated. Which mutant has
the largest difference in the number ofatoms compared to the wild type?
(A) Ser-Cys
(B) Tyr + Phe
(C) Lys 4 Ala
(D) Arg+ Lys
4. The major storage polysaccharide of mammals is found in highesi amounts in
which organ?
(A) Kidney
(B) Liver
(C) Spleen
(D) Pancreas
5. From the following sets, pick h e one that contains exclusively hydrophobic
amino acids
(A) Asp, Glu, Lys, Arg, Ser
(B) Arg, Phe, Tyr, Trp, Asn
(C) Ala, IIe, Leu, Phe, Val
(D) Ala, k g , Phe, Leu, Tyr
6. An enzyrne (Molecular weight = 5,500 Da) has a concentration of 93.5 fliter and
maximum velocity of 0.875 M-' ~ e c - ' . What is the specificity constant for the
enzyme and substrate if KM is 0.438 M?
(A) 22-54 M-' ~ e c - '
(B) 1 17.5 M-' ~ e c - '
(C) 6.52 M-' se=-'
@) 225.4 M-' ~ e c * '
7. Which one of the following statements about a circular double stranded DNA
genome having 2 1% adenosine is TRUE?
(A) It has 10.5% guanosine
(B) It has 29% guanosine
(C) It has 2 1 % guanosine
(D) It has 58% guanosine
8. The peplide, Ala-Arg-Gln-Met-Thr-Trp-Lys-Val, was diges ted with cyanogen
bromide to produce
(A) Ala-Arg-Gln-Met + Thr-Trp-Lys-VaI
(B) Ala-Arg-Gln-Met-Thr-Trp + Lys-Val
(C) Ala-Arg + Gln-Met-Thr-Trp-Lys-Val
(D) Ala-Arg-Gln + Met-Thr-Trp-Lys-Val
9. Deficiency of which vitamin causes inefiicient collagen hydroxylation?
(A) Vitamin C
(B) Vitamin A
(C) VitaminB9
(D) Vitarnin Bl
10. Statins reduce cholesterol levels by inhibiting which enzyme?
(A) NADPH oxidase
(B) HMG-CoA reductase
(C) HMG-CoA synthetasc
(D) Mevalonate kinase
1 1. Which enzyrne is involved in non-template dependent nucleic acid synthesis?
(A) DNA polyrnerase 3
(B) DNA polymerase 1
(C) RNA polymerase
(Dl poly (A) polymerase
Attached Files
File Type: pdf IIST Phd entrance exam paper.pdf (269.8 KB, 83 views)


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