16th June 2015 10:48 AM | |
Quick Sam | Re: MSC Chemistry Syllabus of Calcutta University You are looking for the MSc Chemistry syllabus. So I am providing it to you: MSc Chemistry Syllabus of Calcutta University UNIVERSITY OF CALICUT M.Sc. CHEMISTRY CSS PATTERN – SEMESTER I CH1CO1 – THEORETICAL CHEMISTRY – I (4 Credits) (72 h) UNIT I : The Foundations of Quantum Mechanics (9 h) . Historical background of quantum mechanics. Detailed discussion of postulates of quantum mechanics – State function or wave function postulate, Born interpretation of the wave function, well behaved functions, orthonormality of wave functions; Operator postulate, operator algebra, linear and nonlinear operators, Laplacian operator, Hermitian operators and their properties, eigen functions and eigen values of an operator; Eigen value postulate, eigen value equation, eigen functions of commuting operators; Expectation value postulate; Postulate of time - dependent Schrödinger equation of motion, conservative systems and time-independent Schrödinger equation. UNIT II : Quantum mechanics of translational & vibrational motions (9 h). Particle in a one-dimensional box with infinite potential walls, important features of the problem; Free particle in one -dimension; Particle in a one-dimensional box with finite potential walls (or particle in a rectangular well) – tunneling; Particle in a three dimensional box, separation of variables, degeneracy. One-dimensional harmonic oscillator (complete treatment): - Method of power series, Hermite equation and Hermite polynomials, recursion relation, wave functions and energies, important features of the problem, harmonic oscillator model and molecular vibrations. UNIT III : Quantum mechanics of Rotational motion (9 h) . Co-ordinate systems:- Cartesian, cylindrical polar and spherical polar coordinates and their relationships. Rigid rotator (complete treatment): The wave equation in spherical polar coordinates, planar rigid rotor (or particle on a ring), the Phi-equation, solution of the Phi-equation, handling of imaginary wave functions, wave functions in the real form; Non -planar rigid rotor (or particle on a sphere), separation of variables, the Phiequation and the Theta-equation and their solutions, Legendre and associated Legendre equations, Legendre and associated Legendre polynomials, Rodrigue's formula, spherical harmonics (imaginary and real forms), polar diagrams of sphe rical harmonics. Quantization of angular momentum, quantum mechanical operators corresponding to angular momenta ( L x, Ly, Lz, ), commutation relations between these operators, spherical harmonics as eigen functions of angular momentum operators L x & Lz, Ladder operator method for angular momentum, space quantization. UNIT IV : Quantum Mechanics of Hydrogen -like Atoms (9h). Potential energy of hydrogen-like systems, the wave equation in spherical polar coordinates, separation of variables, the R, Theta a nd Phi equations and their solutions, Laguerre and associated Laguerre polynomials, wave functions and energies of hydrogen-like atoms, orbitals, radial functions and radial distribution functions and their plots. angular functions (spherical harmonics) an d their plots. The postulate of spin by Uhlenbeck and Goudsmith, Dirac's relativistic equation for hydrogen atom and discovery of spin (qualitative treatment), spin orbitals, construction of spin orbitals from orbitals and spin functions. UNIT V : Approximation methods in quantum mechanics (9 h) . Manybody problem and the need of approximation methods; Independent particle model; Variation method – variation theorem with proof, illustration of variation theorem using a trial function [e.g., x (a-x)] for particle in a 1D-box and using the trial function e -r2 for the hydrogen atom, variation treatment for the ground state of helium atom; Perturbation method – time-independent perturbation method (non-degenerate case only), illustration by application to particle in a ID-box with slanted bottom, perturbation treatment of the ground state of the helium atom. UNIT VI : Quantum mechanics of many -electron atoms (9 h). Hartree Self-Consistent Field method for atoms; Spin orbitals for many electron atoms, symmetric and antisymmetric wave functions, Pauli's antisymmetry principle; Slater determinants; Hartree -Fock Self- Consistent Field (HF-SCF) method for atoms, Hartree -Fock equations (derivation not required) & the Fock operator; Roothan's concept of basis functions – Slater type orbitals (STO) and Gaussian type orbitals (GTO). UNIT VII : Chemical bonding in diatomic molecule (9 h) . Schrödinger equation for a molecule, Born – Oppenheimer approximation; Valence Bond (VB) theory – VB theory of H2 molecule, singlet and triplet state functions (spin orbitals) of H 2; Molecular Orbital (MO) theory – MO theory of H2+ ion, MO theory of H2 molecule, MO treatment of homonuclear diatomic molecules – Li2, Be2, C2, N2, O2 & F2 and hetero nuclear diatomic molecules – LiH, CO, NO & HF, bond order, correlation diagrams, non-crossing rule; Spectroscopic term symbols for diatomic molecules; Comparison of MO and VB theories. UNIT VIII : Chemical Bonding in polyatomic molecules (9 h) . Hybridization – quantum mechanical treatment of sp, sp2 & sp3 hybridisation; Semi empirical MO treatment of planar conjugated molecules – Hückel Molecular Orbital (HMO) theory of ethylene, butadiene & allylic anion, charge distributions and bond orders from the coefficients of HMO, calculation of free valence, HMO theory of aromatic hydrocarbons (benzene); formula for the roots of the Hückel determinantal equation, Frost -Hückel circle mnemonic device for cyclic polyenes. References 1. F.L. Pilar, Elementary Quantum Chemistry , McGraw-Hill, 1968. 2. I.N. Levine, Quantum Chemistry, 6th Edition, Pearson Education Inc., 2009. 3. I.N. Levine, Student Solutions Manual for Quantum Chemistry 6 th Edition, Pearson Education Inc., 2009. 4. P.W. Atkins and R.S. Friedman, Molecular Quantum Mechanics , 4th Edition, Oxford University Press, 2005. 5. M.W. Hanna, Quantum Mechanics in Chemistry , 2nd Edition, W.A. Benjamin Inc., 1969. 6. Donald, A. McQuarrie, Quantum Chemistry, University Science Books, 1983 (first Indian edition, Viva books, 2003). 7. Thomas Engel, Quantum Chemistry & Spectro scopy, Pearson Education, 2006. 8. J.P. Lowe, Quantum Chemistry, 2nd Edition, Academic Press Inc., 1993. 9. Horia Metiu, Physical Chemistry – Quantum Mechanics, Taylor & Francis, 2006. 10. A.K. Chandra, Introduction to Quantum Chemistry , 4th Edition, Tata McGraw-Hill, 1994. 11. L. Pauling and E.B. Wilson, Introduction to Quantum Mechanics , McGraw-Hill, 1935 (A good source book for many derivations). 12. R.L. Flurry, Jr., Quantum Chemistry, Prentice Hall, 1983. 13. R.K. Prasad, Quantum Chemistry, 3rd Edition, New Age International, 2006. 14. M.S. Pathania, Quantum Chemistry and Spectroscopy (Problems & Solutions), Vishal Publications, 1984. 15. C.N. Datta, Lectures on Chemical Bonding and Quantum Chemistry , Prism Books Pvt. Ltd., 1998. 16. Jack Simons, An Introduction to Theoretical Che mistry, Cambridge University Press, 2003. UNIVERSITY OF CALICUT M.Sc. CHEMISTRY CSS SYSTEM – SEMESTER I CH1CO2 – INORGANIC CHEMISTRY – I - 4 CREDIT (72 h) UNIT I : (9 h). Acid base theories – strength of acids and bases, Factors governing acid strength, solvent leveling, effect of hard and soft acids and bases, super acids, chemistry of non aqueous solvents – liquid NH3, SO2, H2SO4 and HF. Heterogeneous acid -base reactions – surface acidity, Solid and molten acids in industrial processes. UNIT II (9 h). Electron deficient compounds – synthesis, reactions, structure and bonding. Boron hydrides, styx numbers, Boron cluster compounds, Wade's rule, Hydroborate anions, Organoboranes and hydroboration, Polyhedral anions, Carboranes, Metalloboranes, Borazine s and Borides. UNIT III (9 h). Phosphorus-nitrogen compounds; Phosphazene, cyclo- and linear phosphazenes. Phosphorus -sulphur compounds; Sulphurnitrogen ring and chain compounds – synthesis, structure, bonding and uses. Silicones – Synthesis, structure and applications. Carbides and silicides. Silicates and alumino silicates – framework of silicates, structure and application, UNIT IV (9 h). Standard reduction potentials and their diagrammatic representations Ellingham diagram. Latimer and Frost diagram . Pourbaux diagrams. Metallic corrosion and passivity, Isopoly and heteropoly anions of early transition metals. UNIT V (9 h). Errors and treatment of analytical data, limitations of analytical methods, accuracy and precision, classification and minimization of errors, significant figures, standard deviation, statistical treatment of data, students tests, confidence limit, Q test, Method of least squares. UNIT VI (9 h). Theory Indicators, Acid-base, redox, absorption, complexometric and luminescent indica tors, Titrations in non-aqueous solvents, Complex formation titrations, Principles of gravimetric analysis, Formation and properties of precipitates, Co -precipitation, Precipitation from homogeneous solution, Washing of the precipitate, ignition of the precipitate, Fractional precipitation, Organic precipitants. UNIT VII (9 h). Introduction to co-ordination Chemistry – Stereochemistry of coordination compounds. Formation constants, factors influencing stability, methods of determination of stability consta nts, stabilization of unusual oxidation states. Chelate -macrocyclic and template effects, ambidentate and macrocyclic ligands. Valence bond theory and its limitations. UNIT VIII (9 h). The crystal field and ligand field theories, orbital splitting in octahedral, tetrahedral and square planar fields. Factors affecting crystal field splitting, spectrochemical and nephelauxetic series, Racah parameters, Jahn-Teller effect, MO theory – composition of ligand group orbitals. MO diagram of complexes with and wi thout pi-bonding. The f-orbitals and f-block complexes. References 1. D.F. Shriver, P.W. Atkins and C.H. Langford, Inorganic Chemistry, ELBS, 1990. 2. J.E. Huheey, e.A. Keiter and R.L. Keiter, Inorganic Chemistry, Principles, Structure and Reactivity , Pearson Education, 1990. 3. F.A. Cotton and G. Wilkinson, Advanced Inorganic Chemistry , 5th Edition, John Wiley and Sons, 1988. 4. B. Douglous, D.H. McDanials and J.J. Alexander, Concepts and Models in Inorganic Chemistry, Oxford and IBH Publishing Co. Pvt. Ltd., 1965. 5. L.V. Azaroff, Introduction to Solids, McGraw Hill, NY, 1960. 6. G.H. Jeffery, J. Bassett, J. Mendham and R.C. Denny, Vogel's Text book of Quantitative Chemicals Analysis , 5th Edition, ELBS, 1989. 7. Skoog, West and Holler, Fundamentals of Analytical Chenustry, 8th Edition, Thomson and Brooks, 2004. 8. C.E. Houecroft, Cluster molecules of p-block elements. Oxford Scientific Publications, 1994. 9. D. Sutton, Electronic Spectra of Transition Metal Complexes , McGraw Hill, 1968. 10. J.C. Blair, Jr. (Ed.), The Chemistry of Coordination Compounds , Reinhold Pub. Cor., 1960. 11. L.F. Lindoy, The Chemistry of Macrocyclic Ligands and Complexes , Cambridge University Press, 1989. 12. J.D. Lee, Concise Inorganic Chemistry, 5th Edition, Oxford University Press, 2008. 13. Wahid U Malik, G.D. Tuli, R.D. Madan, Selected Topics in Inorganic Chemistry, S. Chand and Company Reprint 2009. UNIVERSITY OF CALICUT M.Sc. CHEMISTRY(CSS PATTERN) – SEMESTER I CH1CO3 – ORGANIC CHEMISTRY – I (4 Credits) (72 h) UNIT I : (9 h). Delocalized chemical bonding, Electron Delocalization, Resonance and Aromaticity: Qualitative application of Huckel MO theory and perturbation theory to systems containing delocalized electrons. Delocalized electrons and Resonance, Resonance hybrid an d resonance energy. Criteria for Aromaticity and Antiaromaticity, MO description of Aromaticity and Antiaromaticity. Homoaromaticity, Mobius twist and Aromaticity. Aromaticity of Annuelens and heteroannulenes, Fullerines, and fused ring systems. Stability of benzylic cations and radicals. Effect of delocalized electrons on pKa. Hydrogen bonding: Inter- and intramlecular hydrogen bonding. Range of the energy of hydrogen bonding. Effect of hydrogen bond on conformation, physical and chemical properties of o rganic compounds, vilatility, acidity, basicity and stability of hydrates of carbonyl compounds. Stabilization of hydrates of glyoxal and chloral, and ninhydrin. High acid strength of maleic acid compared to fumaric acid. UNIT II : (9 h). Basic concepts in the study of organic reaction mechanisms: Application of Experimental criteria to mechanistic studies, Thermodynamic and kinetic data, Curtius -Hammet principles, Kinetic versus thermodynamic control. Acidity constant, Hammet acidity function. Reactive intermediates and their characterizatin. Isotope effect (labeling experiments), Stereochemical correlations. Neighbouring group participation, participation of carboxylate ion, halogen, hydroxyl group, acetoxy group, phenyl group and pi -bond. Structure and reactivity, Transition state theory, Potential energy vs Reaction co-ordinate curve, Substituent effects (inductive, mesomeric, inductomeric, electomeric and field effects) on reactivity. Qualitative study of substitution effects in SN1 -SN2 reactions. Semiquantitative study of substituent effects on the acidity of carboxylic acids. Quantitative correlation of substituent effects on reactivity. Linear free energy relationships. Hammet and Taft equation for polar effects and Taft's steric, substituent constant for steric effect. References: (Unit I and II) 1. J. March, Advanced Organic Chemistry , 4th Edition, John Wiley and Sons, 1992. 2. T.H. Lowry and K.S. Richardson, Mechanism and Theory in Organic Chemistry, Harper Collins, 1987. 3. F.A. Carey and R.J. Sundberg, Advanced Organic Chemistry (Parts A & B), 3rd Edition, Plenum Press, 1990. 4. R.A.Y. Jones, Physical and Mechanistic Organic Chemistry , Cambridge University Press, 1979. UNIT III : Isomerism-I (9 h): Concept of Chirality, Recognition of symmetry elements and chiral structures, Conditions for optical activity, Optical purity, Specific rotation and its variation in sign and magnitude under different conditions, Relative and absolute configurations, Fisher projection formula, Sequence rule – R and S notations in cyclic and acyclic compounds. Optical isomerism of compounds containing one or more asymmetric carbon atoms, Enantiotopic, Homotopic, Diastereotopic hydrogen atoms, Prochiral centre. Optical isomerism in Biphenyls, Allenes and Nitrogen and Sul phur compounds, Conditions for optical activity, R and S notations. Restricted rotation in biphenyls – Molecular overcrowding. Chirality due to folding of helical structures. Geometrical isomerism – E and Z notation of compounds with one and more double bonds in acyclic systems. Methods of determination of the configuration of geometrical isomers in acyclic acid cyclic systems, inter conversion of geometrical isomers. Stereochemistry of Aldoximes and ketomines – Naming – isomerism – methods of determining configurations. UNIT IV : Isomerism-II (9 h): Asymmetric Synthesis: The chiral pool: Alpha amino acids in the synthesis of benzodiazepines, carbohydrates (benzyl D mannose to Swainsonine/preparation of tomolol from D - mannitol), Felkin-Ahn model and Cram's chelation control. Chiral auxiliaries: Oxazolidinones, Chiral sulfoxides in controlling the reduction of ketones, Camphor derivative in Diels Alder reaction and radical reactions. Chiral reagents: BINOL, tartrates, lithium di(1 -phenyl ethyl) amide. Chiral catalysts: Rhodium and ruthenium catalysts with chiral phosphine ligands like (R)BINAP, (R,R)DIOP. Enzymatic methods. References 1. J. March, Advanced Organic Chemistry , 4th Edition, John Wiley and Sons, 1992. 2. Nasipuri, Stereochemistry of Organic Compounds, 2nd Edition, New Age International. 3. Kalsi, Stereochemistry of Organic Compounds , Wiley Eastern. 4. J. Clayden, N. Greeves, S. Warren and P. Wothers, Organic Chemistry, Oxford University Press, 2001. 5. E. Eliel and S.H. Wilen, Stereochemistry of Organic Compounds, John Wiley, 1994. UNIT V : Conformational Analysis – I (9 h): Difference between configuration and confirmation. Internal factors affecting the stability of molecules – dipole interaction, bond opposition strain, bond angle strain. Perspective and Newman projections – representation of different conformations. Conformation of acyclic compounds – Ethane, n-butane, alkene dihalides,glycols, chloro hydrines, tartaric acid, erythro and threo isomers, aldehydesand ketones (acetaldehyde, acetone). Interconversion of axial and equatorial bonds in chair conformation – distance between the various H atoms and C atoms in both chair and boat conformations. Monosubstituted cyclohexane – methyl and t-butyl cyclohexanes – flexible and rigid systems . Conformation of disubstituted cyclohexanes (1:1; 1:2; 1:3 and 1:4). Conformation of substituted cyclohexanone -2-bromocyclohexanone, dibromocyclo hexanone, (cis & trans), 2-bromo-4,4-dimethyl cyclohexanone. Anchoring group and conformationaly biased molec ules. Conformations of 1:4 cis and trans disubstituted cyclohexanes in which one of the substituent is 1-butyl and their importance in assessing the reactivity of an axial or equatorial substituent. Conformations of decaline, adamentane, sucrose and lactos e. UNIT VI : Conformational Analysis – II (9 h): Effect of conformation on the course and rate of reactions in (a) Debromination of dl and meso 2,3 - dibromobutane or stilbene dibromide using KI. (b) Semipinacolic deamination of erythro and threo 1,2 -diphenyl-1-(p-chlorophenyl)-2- amino ethanol. (c) Action of methyl magnesium bromide on 2 - phenylpropionaldehyde (Stereo chemical direction of asymmeetric induction). (d) Dehydrohalogination of stilbenedihalide (dl and meso) and erythreo threo- bromo-1,2-diphenyl propane. Effect of conformation on the course and rate of reactions in cyclohexane systems illustrated by: (a) S N2 and SN1 reactions for (i) an axial substituent, and (ii) an equatorial substituent in flexible and rigid systems. (b) E1, E2 eliminations il lustrated by the following compounds. (i) 4-t-Butylcyclohexyl tosylate (cis and trans) (ii) 2 - Phenylcyclohexanol (cis and trans) (iii) Menthyl and neomenthyl chlorides and benzene hexachlorides. (c) Pyrolytic elimination of esters (cis elimination) (d) Semipinacolic deamination of cis and trans -2- aminocyclohexanol (e) Esterification of axial as well as equatorial hydroxyl and hydrolysis of their esters in rigid and flexible systems. (Compare the rate of esterification of methanol, isomenthol, neomenthol and neoisomenthol). (f) Esterification of axial as well as equatorial carboxyl groups and hydrolysis of their esters. (g) Hydrolysis of axial and equatorial tosylates. (h) Oxidation of secondary axial and equatorial hydroxyl group to ketones by chronic acid. UNIT VII : (i) Reactions of Carbon -heteromultiple bonds (7 h): Addition of carbon-oxygen multiple bond: Addition of water, alcohols, amines and hydrazine. Aldol, Perkin, Clainson, Dieckmann, Stobbe and benzoin condensation. Darzons, Knoevenagel, Reforma tosky, Wittig, Cannizaro, Mannich and Prins reactions. MPV reduction and Oppenaur oxidation. Cram's rule. Hydrolysis, alcoholysis and reduction of nitriles. Ritter reactin and Thorpe condensation. (ii) Esterification and Hydrolysis (2 h) : Mechanism of Ester hydrolysis and esterification, Acyl -oxygen and alkyl oxygen cleavage. Esterification of axial and equatorial alcohols and acids – their hydrolysis. References 1. J. March, Advanced Organic Chemistry , 4th Edition, John Wiley and Sons, 1992. 2. Morrison & Boyd, Organic Chemistry, Prentice Hall. 3. F.A. Carey and R.J. Sundberg, Advanced Organic Chemistry *Parts A & B), 3rd Edition, Plenum Press, 1990. 4. E.S. Gould, Mechanism and structure in organic chemistry , Holt, Rinehart and Winston, 1959. UNIT VIII : Introduction to Polymer Chemistry ( 9 h): Classes of polymers, Synthetic and biopolymers. Synthetic polymers: Chain reaction polymerization and step reaction polymerization. Linear, crosslinked and network polymers. Copolymers, Free -radical and ionic polymerization. Natural and synthetic rubbers. Biopolymers: Primary, secondary and tertiary structure of proteins, Solid phase peptide synthesis, Protecting groups, Sequence determination of peptides and proteins, Structure and synthesis of glutathione, Structure of RNA and DNA, Structure of cellulose and starch, Conversion of cellulose to Rayon. References 1. Saunders, Organic Polymer Chemistry, Chapman and Hall. 2. S.H. Pine, J.B. Hendrickson, D.J. Cram and G.S. Hammond, Organic Chemistry, McGraw Hill International B ook Company, 1981. 3. I.L. Finar, Organic Chemistry, Vol. II, 5th Edition, ELBS, 1975. 4. Jordean, The Chemistry of Nucleic Acids , Buttorworths. Contact: Calcutta University Senate House, 87/1, College Street, Kolkata, West Bengal 700073 033 2241 0071 Map: [MAP]Calcutta University[/MAP] For full syllabus download this Attachment: |
16th June 2015 09:47 AM | |
Unregistered | MSC Chemistry Syllabus of Calcutta University Hello, I am looking for the syllabus of the MSC Chemistry of the Calcutta University. So can you please provide me the syllabus of the MSC Chemistry including the contact details of the University?? |