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  #1  
29th March 2016, 03:20 PM
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Mda-mb-231 atcc

HI I would like to know what MDA-MB-231 ATCC is and the details like the characteristics as well as the general information about it?
  #2  
29th March 2016, 03:27 PM
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Join Date: May 2012
Re: Mda-mb-231 atcc

MDA-MB-231 (ATCC® Cat. No. HTB-26™) is an epithelial, bosom adenocarcinoma cell line that was gotten from a metastatic pleural emission. ATCC accomplished transfection efficiencies of roughly 90%,

General Information:

Organism
Homo sapiens, human
Tissue mammary gland/breast; derived from metastatic site: pleural effusion

Cell Type
epithelial

Product Format
frozen

Morphology
epithelial

Culture Properties
adherent

Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Disease
adenocarcinoma

Age
51 years adult

Gender
female

Ethnicity
Caucasian

Applications
These cells are a suitable transfection host

Storage Conditions
liquid nitrogen vapor phase



Receptor Expression
epidermal growth factor (EGF), expressed
transforming growth factor alpha (TGF alpha), expressed

Oncogene
The cells express the WNT7B oncogene. Ref

Tumorigenic
Yes

Effects
Yes, in ALS treated BALB/c mice, forms poorly differentiated adenocarcinoma (grade III)
Yes, in nude mice, forms poorly differentiated adenocarcinoma (grade III)


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