#1
25th August 2014, 03:51 PM
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Entrance Exam syllabus for Ph.D Chemistry
I am looking for Ph.D Chemistry entrance exam syllabus of National Institute of Technology, Jalandhar, please provide here.
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#2
26th August 2014, 08:56 AM
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Re: Entrance Exam syllabus for Ph.D Chemistry
You are looking for National Institute of Technology, Jalandhar Ph.D Chemistry entrance exam syllabus, i am giving here: 1. Stereochemistry: Configuration and chirality, optical isomerism, R,S-convention, enantiotopic and diastereotopic groups, methods of resolution, asymmetric synthesis. Geometrical isomerism E,Z-convention. Conformational analysis; effect of conformation on reactivity. 2. Reactive Intermediatates: Generation, structure and reactions of carbocations, carbanions, nitrenes and free radicals. 3. Nucleophilic substitution: Mechanisms, Classical and nonclassical carbocations. Reactivity effects of substrate structure, attacking nucleophile, leaving group and reaction medium. Aromatic Nucleophilic substitution: Mechanisms, reactivity, effect of substrate structure, leaving group and attacking nucleophile. 4. Electrophilic Substitution: Mechanisms, effect of substrates, leaving group and the solvent polarity on the reactivity. Aromatic- the Arenium ion mechanism, orientation and reactivity, energy profile diagrams, quantitative treatment of reactivity in substrates and electrophiles. 5. Addition to Carbon-Carbon Multiple Bonds: Mechanism, direction and stereochemistry, addition to alkenes and alkynes, Transition metal organometallics. 6. Addition to Carbon-hetero Multiple Bonds; Mechanism of metal hydride reduction of saturated and unsaturated carbonyl compounds, acids, esters and nitriles, Addition of Grignard reagents. 6. Elimination Reactions: Reaction mechanism, Direction, stereochemistry, formation of alkenes , alkynes and other multiple bonds. 7. Ring Expansion and Contraction: Demjanov ring expansion, Favorskii rearrangement. REFERENCES: 1. Stereochemistry of Carbon Compounds by E. J. Eliel, Tata Mc Graw Hill, 2002. 2. Stereochemistry of Organic Compounds by D. Nasipuri, Wiley, 1994. 3. Organic Chemistry by J. M. Hornback, Books Coley, 1998. 4. Organic Chemistry by P. Y. Bruice, Prentice Hall , 1998. 5. Organic Reaction and their Mechanisms by P. S. Kalsi, New Age International Publishers , 2nd edition, 2007. 6. Modern Synthetic Reaction by H. O. House, W. A. Benjamin, Inc, 1972. Thermodynamics and Chemical Kinetics 1. Law of Thermodynamics: Exact and Inexact Differentials, Cyclic Rule, Reciprocity Characteristics, Homogenous Function, Euler’s Theorm, third Law of thermodynamics, Nernst Heat theorm, Thermodynamic Properties at Absolute Zero, Entropy & Third Law of Thermodynamics. 2. System of Variable Compositions: Partial Molar Quantities, Chemical Potential and its Variation with Temperature and Pressure, Chemical Potential of Real Gases & Fugacity, Chemical Potential in ideal Gas Mixture, Concept of Escaping Tendency. 3. Physical Transformation of Pure Substances and Simple Mixtures: Phase Diagrams, Phase Stability and Phase Transitions, The Physical Liquid Surface, Thermodynamics function of Mixing. 4. Chemical Equilibrium: Spontaneous Chemical Reactions, Response of Equilibria to the Conditions, Thermodynamic Properties of Ions in Solution. 5. Chemical Kinetics: Collision theory of Reaction Rates, Arrhenius Equation and Activated Complex Theory, Comparison of Collision and Activated Complex Theory. 6. Advanced Chemical Kinetics: Applications of Activated Complex Theory, RRK and RRKM Theory, Theories of Unimolecular Reactions. 7. Dynamics of Complex Reactions: Ion-Ion Reactions, Ion-Dipole reactions, Enzyme Kinetics, polymerization Kinetics, Kinetic Salt, Salt Effect. 8. Dynamics of Fast Reactions: General Treatment of Chain Reactions, Theories of Branching Chain and Explosion, Flow Methods, Relaxation Techniques, Flash Photolysis. REFERENCES: 1. Thermodynamics A core Course by R. C. Srivastva, S. K. Saha, A. K. Jain, PH I, New Delhi, 2007. 2. Physical Chemistry, P. Atkins, J. D. Paula, Oxford University Press, 7th Indian Edition, 2007. 3. An Introduction to Chemical Thermodynamics by R. P. Rastogi & R. R. Mishra, Vikas Publishing House, 6th Edition , 2007. 4. Chemical Kinetics by Keith J. Laidler, Pearson Education, 3rd Edition. 5. Chemical Kinetics by K. A. Corrnors, VCH, 1998. 6. Physical Chemistry by R. S. Berry, S. A. Rice & J. Ross, Oxford University Press 2nd Edition, 2000. 7. Fast Reactions J. N. Bradley, Oxford University press, 1975. Main Group Chemistry 1. Chemistry of hydrogen: Ionized forms of Hydrogen, Protonic acids and bases, The Hydrogen Bond, its influence on Properties and influence on structure, Strength of hydrogen bonds and theoretical description. 2. Chemistry of S-block metals: Hydrides, Halides, Oxides, Peroxides, Superoxides, Suboxides, Hydroxides, Oxoacid salts Complexes Crowns and Crypts of Alkali Metals and coordination complexes of Alkaline Earth Metals. 3. Chemistry of Boron and Aluminum: Boranes, Bonding in boranes, topology of boranes, synthesis and reactivity. Carboranes and mettallocarboranes,Borazine and boron nitride. Chemistry of Aluminum Halides. Aluminum Alkyls. Low oxidation state Al compounds. 4. Chemistry of Silicon: Organosilicon Compounds. Sillicates and Aluminosilicates. Low-valent Silicon compounds, silylenes and R3Si+. 5. Inorganic rings, Cages, Clusters and Polymers: Phosophazenes, Cyclophosphazenes , Polyphosphozenes and the polymers derived from them. Polysilanes. 6. Chemistry of halogens and nobel gases: Inter Halogens, Poly Halide Anions, CFC’s , Ozone layer and Clathrates. 7. Chemistry of group 12 elements: Halides & Oxygen compounds, chalcogenides & Related compounds, low-valent compounds & Formation of coordination complexes. References: 1. Main Group Chemistry, W. Henderson, Royal Society of Chemistry, 2000. 2. Advanced Inorganic Chemistry, F. A. Cotton and G. Wilkinson et. al, Sixth edition John Wiley & Sons, 2003. 3. Inorganic Chemistry, J. E. Huheey et. al, Fourth edition, Pearson, 2005. 4. Concepts & Model of Inorganic Chemistry, B. Douglas et. al, 3rd John Wiley & Sons, 2001. 5. Chemistry of Elements, N. N. Greenwood, Pergamon Press, 2000. 6. Inorganic Chemistry 4th edition D. F. Shriver and P. W. Atkins, Oxford University, Oxford, 2006. Basic Biological Chemistry 1. Cell :Types of cells and structure and functions 2. Introduction to Biomolecules: Carbohydrates, Proteins, Amino acids, Lipids and phospholipids, Biological membranes, transport across membranes. 3. Nucleic Acids: Base pairing, double helices, DNA replication, transcription and translation. 4. Enzymes: enzyme kinetics and mechanism, nature and application of enzymes. 5. Biotechnology and its Applications: Genetic engineering, Potential laboratory biohazards of genetic engineering, Polymerase chain reaction, Pharmaceutical and biopharmaceuticals, Vaccines and monoclonal bodies ,Waster water and sewage treatment, landfill technologies. 6. Transmission of Nervous impulse & mechanism: Neurons and its Structure, Nerve Transmission, Nerve poisons. REFERENCES: 1. Biotechnology, by J. E. smith, 4th edition, Cambridge, 2004. 2. Principle of Biochemistry by Lehinger, Nelson and Cox, CBS publisher 1993. 3. Principles of Biochemistry ,by T.N. Pattabiraman , Gajanana book publishers and Distributors, 1993. Quantum Chemistry 1. Foundations of Quantum Mechanics: Operators, Postulates, Matrices and Schrodinger Equation. 2. Linear Motion and harmonic Oscillators: Translational, harmonic, particle in a box a penetration through barriers. 3. Rotational motion and hydrogen atom: Particle in a ring & on a sphere, motion in a columbic field. 4. Angular momentum: Angular momentum operators, definition of states, Composite systems. 5. Techniques of Approximation: Perturbation theory, variation theory, HF theoretic, time dependent perturbation. 6. Atomic Structure: Hydrogen, Helium & multi electron system. 7. Molecular Structure: Born- openheimer approximation MO theory of mono, dia & polyatomic molecules, band theory of solids. 8. Electronic Structure: SCF method electron correlation Density functional theory, gradient method, semi-empirical methods & software packages for calculations. 9. Molecular Rotation & Vibration: Rotation & Vibration in diatomic, polyatomic molecules. 10. Electronic Transition in molecules: Rotational, Vibronic and electronic states & fates of excited species. REFERENCES: 1. Quantum Chemistry, I. N. Levine, Prentice Hall, 2000. 2. Molecular Quantum Mechanics, P. W. Atkins and R. S. Friendman, OUP, 1997. 3. Physical Chemistry-by P. W. Atkins, Oxford University Press, 1990. 4. Introduction to Quantum Mechanics with Applications to Chemistry, L. Pauling and E. B. Wilson, Dover NY, 1985. Pharmaceutical Chemistry 1. Drug Discovery and Drug Development: Introduction, Present and Past, Drugs and the medicinal chemist, Classification of drugs, Drug targets specification, Choice of Bioassay, In Vivo and in Vitro tests, Pit falls. 2. Drug Action at Receptors: Receptor role, Neuro-transmitters and Hormones, Change of shape by the receptors, Design of Agonists and Antagonists, Drug action on DNA and RNA. 3. Drug Design, Drug-Target Interactions: Introduction, Variation of Substituent, Expansion of the Structure, Chain expansion/Contractions, Ring expansion/Contractions, Ring Variation, Ring Fusions, Isosteres. 4. Pharmacokinetics: Drug distribution and survival, Pharmacokinetic issues in drug design like Chemical and Metabolic stability, Hydrophilic / hydrophobic balance, Ionization, size and number of hydrogen bonding interactions, Drug dose levels, solubility and membrane permeability, variation of different groups to alter polarity. 5. Prodrugs: Introduction, Effect of prodrugs on: improved membrane permeability, prolonged drug activity, masking drug toxicity and side effects, increased chemical stability, targeting of drugs, prodrugs activation by external influence. 6. Drug administration: Introduction, oral administration, sublingual administration, rectal administration, epithelial administration, inhalation, injection and implants. REFERENCES: 1. Textbook of Pharmacology, W. C. Bowman, and M. J. Rand, Blackwell Scientific 1980. 2. Medicinal Chemistry-the role of organic chemistry in drug, C. R. Ganellin, and S. M. Roberts, , research, Academic Press 1993. 3. Medicinal Chemistry-principles and practice, F. D. King, , The Royal Society of Chemistry 1994. 4. Burger’s Medicinal Chemistry and drug discovery, M. E. Wolff, 5th edition Volume 1-5. Wiley 1995. For detailed syllabus here is attachment: |
#3
20th March 2015, 08:46 AM
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Re: Entrance Exam syllabus for Ph.D Chemistry
I want to crack Ph.D Chemistry Entrance Exam . Will you please provide the Ph.D Chemistry Entrance Exam syllabus for preparation ?
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#4
20th March 2015, 08:47 AM
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Re: Entrance Exam syllabus for Ph.D Chemistry
Here I am providing the Ph.D Chemistry Entrance Exam syllabus for preparation which you are looking for . Stereochemistry Baldwin’s Rule and Dunitz’s angle of attack Cieplak Model Felkin-Ahn Model Optical purity Sterospecific and stereoselective synthesis Conformation analysis of cycloalkanes Cram’s Model Enatiotopic and diastereotopic atoms, groups & faces Organic Reaction Mechanisms Arndt-Eistert Synthesis Beckmann Rearrangement Pinacol-Pinacolone Rearrangement Sandmeyer reaction Smiles Rearrangement Wagner-Meerwein Rearrangement Benzil-Benzilic acid Carbanions Carbenes Favorskii Rearrangement Free radicals Gattermann-Koch reaction Hunsdieker reaction Mechanism of nucleophilic substitution Nitrenes Oxidation and Reduction Baeyer Villiger Oxidation Catalytic Hydrogenation Prevost Reaction Swern oxidation Wolf Kishner Reduction Clemmenson’s Reduction Metal Reductions Meerwin Pondorf Varely Reduction Oppenauer oxidation Heterocyclic Chemistry Diels-Alder Reaction Pal-Knorr synthesis Principles of heterocyclic synthesis Chromatography Classification of stationary and mobile phase Principle and examples of detection methods Thin Layer Chromatography (TLC) Column Chromatography Normal and Reverse Phase Chromatography Paper Chromatography Preparative TLC Reaction Mechanism of Transition Metal Complexes Acid hydrolysis Application of valence bond and crystal field theory Redox reactions Substitution reaction in square complexes Trans effect Base hydrolysis Electron transfer reactions Energy profile of a reaction Kinetics of octahedral substitution Reactivity of metal complexes Metal carbonyls and related complexes Structure and bonding Structure and bonding of transition metal complexes Synthesis, reaction and vibrational spectra Metal-Ligand Bonding Concept of a Ligand field Scope of Ligand field theory Qualitative demonstration of ligand field effect Introductory Quantum Chemistry Black body radiation Emergence of quantum mechanics Planck’s concept of quantization Planck’s equation Uncertainty principle Wave particle duality Electrochemistry Debye-Huckel Theory Derivation of Debye-Huckel-Onsager equation Primary & secondary cell Fuel cell Potentiometric titrations Determination of pH and solubility product Thermodynamics Batteries Chemical kinetics Activation parameters and their significance Catalyst Collision theory Complex reactions Transition state theory Unimolecular reactions and Lindamann’s theory Correlations for nucleophillic reactions Eyring equation Taft four-parameter equation The Swain – Scott equation and the Edward equation Theories of reaction rates Thermodynamic formulation of transition state theory Thermodynamics First and II laws of thermodynamics Concept of entropy-entropy Entropy changes in various processes Entropy as a function of V and T, P and T Clapeyron equation Clausius-Clapeyron equation Closed system Chemical potential of ideal gases Ideal-gas reaction equilibrium Hoff equation Entropy change in isolated systems Entropy changes on mixing of ideal gases Clausius inequality Entropy change as criterion for spontaneity and equilibrium Third law of thermodynamics Evaluation of absolute entropies Standard entropies and entropy changes of chemical reactions Helmholtz and Gibbs Phase equilibrium |
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