Centre for Applied Genetics Bangalore University

What Courses offers by Centre for Applied Genetics of Bangalore University? Who is the HOD of the Centre for Applied Genetics? I am looking for Ph.d in Applied Genetics from the Bangalore University. So is the University offering the following programs or not? Give me prospectus for Ph.D Programs in PDF Format.

Can you provide me the syllabus of Semester I of the Master of Science (Applied Genetics) program offered by Bangalore University, Mysore?

[pooja]

The syllabus of Semester I of the Master of Science (Applied Genetics) program offered by Bangalore University, Mysore is as follows:

THEORY SYLLABUS
I SEMESTER
PAPER-HCT-101: CELL BIOLOGY
UNIT I
Membrane systems and organelles:
Plasma membrane: Structure and chemical composition: Fluid-mosaic model. Transport across membranes: Diffusion, active transport, co-transport and bulk transport, Membrane potentials resting potential and types of propagation of action potentials, liposomes.

Cell organelles: Structure, composition and functions of cell organelles:
Endoplasmic reticulum, Golgi complex, Lysosomes, Mitochondria, Chloroplast and nucleus

UNIT II
Cellular interactions and their environment:
Interaction of cells with non-cellular substrates: The extra cellular space, the extracellular matrix, collagens, proteoglycans, fibronectin, laminin and other proteins, Integrins, focal adhesions and hemidesmosomes.
Interactions of cells with other cells: Selectin, immunoglobulin super family and integrin super family, cadherins, Junctions: tight junctions, gap junctions and desmosomes, Plasmodesmata.
Cell signaling: Communication between cells and their environment, basic characteristics, second messengers and G protein-complex-coupled receptors, role of calcium as a second messenger, receptor tyrosine kinases, MAP kinase cascade.

UNIT III
DNA and its replication:
Chemical nature of the gene- structure of DNA, mechanism of DNA replication in prokaryotes and eukaryotes Non-coding DNA, DNA constancy and C value paradox, mobile genetic elements

Expression of genome:
Transcription: Prokaryotic and eukaryotic transcription, RNA polymerases, general and specific transcription factors, post-transcriptional modifications in RNA( 5' cap formation) transcription termination, poly-adenylation, RNA splicing, Ribozymes, antisense RNA.
Translation: Prokaryotic and Eukaryotic translation, mechanism of initiation, elongation and termination. Co- translational and post-translational modifications of proteins

UNIT IV
Tools of Genetic engineering:
Restriction enzymes, methylases, polymerases, reverse transcriptase, terminal transferase, ligase, kinases and phosphatases. Cloning vectors: plasmids, phages, cosmids, phagemids, viruses and artificial chromosomes Expression vectorsclassification, isolation, purification, salient features and their advantages
Recombination DNA technology: Introduction of recombinant DNAtransformation, transduction, transfection, electroporation, biolistics, microinjection, agronfection, liposome fusion. Application of recombinant DNA technology and Transgenic animals.

REFERENCES
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2 Lodish, H., Berk, A., Zipuosky, L.S., Matsudaira, P., Baltimore, D. & Darnell, J., 2001 Molecular Cell Biology IV Ed., W.H. Freeman & Company.
3 Gilbert, S.F., 1988. Developmental Biology, Sinauer Associates Inc
4 Wilson, E.B. Cell in Development and Inheritance, Mac Millan, N.Y
5 Celis, J.E (Ed.), 1998 Cell Biology: A Laboratory Hand Book Vol. I & II, Academic Press
6 J.Darnell, H.Lodish & D.Baltimore Molecular Cell Biology, Scientific American Books, Inc., USA.
7 Cooper, G.M., 1997. The Cell: A Molecular Approach, Sinauer Associates Inc.
8 Lewin B., 1997 Genes VIII, Oxford University Press, Oxford, N.Y. & Tokyo
9 Garrett & Grisha., 1994 Molecular Aspects of Cell Biology, Sounders, N.Y
10 Karp G., 1999 Cell and Molecular Biology, II Ed., John Wiley & Sons, N.Y