AIIMS biotechnology entrance exam

Hello sir, I want to do M.Sc biotechnology course from AIIMS institute so you give me detail about the entrance exam syllabus?

[Pathak]

There is no specific syllabus for AIIMS biotechnology entrance exam.

The questions will comprise from the Physics, Chemistry, Biology and mathematics subjects.
The questions will also include the 60% of the course you have studied in bachelor degree and 30-40% of class 11th & 12th basics.

All the questions will be of Multiple Choices.

Generally the exam is conducted in the month of July, 2012.

I have completed msc biotechnology and want to do phd in biotechnology can you help by sugessions
thanking you

I want to get information about AIIMS biotechnology entrance exam so will you please provide me that ?

[Quick Sam]

As you want to get information about AIIMS biotechnology entrance exam so here I am giving you same:

Eligibility:

Candidates must posses one of the following qualifications and have secured at least 60% marks for General/OBC candidates (55% marks in case of SC/ST candidates) in aggregate in the qualifying examination:

MBBS/BDS with 55% marks (50% for SC/ST)

Or
B.V. Sc /B. Pharma / B. Sc Degree (3 years) with at least 60% marks (55% for SC/ST)

Application Fee:
General/Unreserved (UR):
Rs. 1000/-

Other Backward Classes (OBC):
Rs.1000/-

Scheduled Caste (SC):
Rs. 800/-

Scheduled Tribe (ST):
Rs. 800/-
AIIMS Biotechnology Entrance Exam Syllabus
OBJECTIVES
At the end of the two years of training programme in Master of Science in Anatomy the student should
be able to:-
1. Acquire comprehensive knowledge of structure and functions of human body, ontogeny of human
development and genetic mechanisms involved in normal and abnormal development, knowledge of
light microscopic and ultrastructure of human body. Knowledge of structure and functional correlation
of nervous system and be able to communicate the same clearly and with precision.
2. Inculcate habit of scientific enquiry and be able to identify lacunae in the existing knowledge in a
given area. Acquire knowledge of modern research techniques and be familiar with the recent
advances in human biology.
Learning Activities, Training And Evaluation
During the course students have formal teaching and are trained for teaching and research
I. Didactic teaching:
Topics in gross anatomy, microanatomy, embryology, neuroanatomy, histochemistry, and genetics,
along with related practical sessions.
II Training
Communication skills – journal club, seminars
Hands on experience – techniques in micro, neuro, gross anatomy, embryology, histochemistry,
genetics, electron and confocal microscopy.
Teaching experience – taking UG classes : demonstrations and practicals for one semesters
(six months)
Educational technology – preparation of AV aids for teaching, posters/manuscripts for presentation
in conferences/workshops and publication in journals. Setting objective
questions – SAQs, MCQs and OSPE. Prepare teaching modules &
museum specimens, casts. Participation in organization of symposia/
workshops.
III. Research
Thesis – progress monitoring every semester.
Presenting paper/poster at conferences/Preparing manuscripts for documentation.
Thesis work presentation at regular intervals.
Thesis submission at the end of 1 &1/2 yrs.
IV. Evaluation of training
Written/practical assessment every semester. Feedback on teaching/training programme.
M.Sc. Anatomy Examinations
Final examination at the end of the course has theory, practical and viva-voce.
Theory
Paper-I : Gross Anatomy with evolution and Comparative Anatomy. Gross Anatomy will include
functional Anatomy. (Section-1)
Paper-II : Microscopic Anatomy, Developmental Anatomy and Genetics. (Section-2)
Paper-III : Neuroanatomy including development and microscopic structure (Section-3)
Practical and Viva
1. Histological techniques, identification light and electron microscopic structure of tissues of body.
2. Slides, specimens of developmental anatomy, genetics, neuroanatomy to assess comprehensive
knowledge in these areas.
Viva-voce on gross anatomy, living anatomy, sectional anatomy and neuroanatomy, developmental
anatomy and genetics.
SECTION – 1
GROSS ANATOMY
COURSE CONTENT
Structure of whole human body in detail, including functional, sectional and radiological anatomy.
PRACTICAL
Dissection of entire body. Preparation of museum specimens, casts, plastination, fixation and preservations
of human body.
SECTION – 2
HISTOLOGY AND HITOCHEMISTRY
COURSE CONTENT
1. Cell Biology: Cytoplasm – Cytoplasmic matrix, cell membrane, cell organelles, cytoskeleton, cell
inclusions, cilia and flagella.
Course and Curriculum of Anatomy 3
Nucleus – nuclear envelope, nuclear matrix, DNA and other components of chromatin, protein
synthesis, nucleolus, nuclear changes indicating cell death.
Cell cycle, mitosis, meiosis, cell renewal. Cellular differentiation and proliferation.
2. Tissues of Body: Light and electron microscopic details and structural basis of function, regeneration
and degeneration.
3. The systems/organs of body – Cellular organization, light and electron microscopic features, structurefunction
correlation, and cellular organization.
PRACTICAL
Preparation of histological sections, light microscopy and its applications, electron microscopy and its
applications, confocal microscopy, histological staining -routine and special stains, identification of
normal and abnormal organelles in electron micrographs , three dimensional interpretation, artifacts
identification.
GENETICS
COURSE CONTENT
Normal and abnormal chromosomes, Molecular genetics, developmental genetics, immunogenetics,
population genetics and genetic counselling.
1. Human Chromosomes - Structure, number and classification, methods of chromosome preparation,
banding patterns. Chromosome abnormalities, Autosomal abnormalities – syndromes, Sex
chromosomal abnormalities – syndromes, Molecular and Cytogenetics.
2. Single gene pattern inheritance, Autosomal and Sex chromosomal patterns of inheritance, Intermediate
pattern and multiple alleles, Mutations, Non Mendelian inheritance, Mitochondrial inheritance, Genomic
imprinting, parental disomy.
3. Multifactorial pattern of inheritance: Criteria for multifactorial inheritance, Teratology, Structure of
gene, Molecular Screening, Cancer Genetics – Haematological malignancies, Cancer Genetics,
Pharmacogenetics.
4. Reproduction Genetics- Male infertility, Female Infertility, assisted reproduction, Preimplanation
genetics, Prenatal diagnosis, Genetic Counselling Ethics and Genetics.
PRACTICAL
DNA Isolation from peripheral blood lymphocytes, Polymerase Chain Reaction (PCR), Fluorescence
In-Situ Hybridization (FISH), Chromosomal Analysis
DEVELOPMENTAL ANATOMY
COURSE CONTENT
Gametogenesis, early human development, general and systemic embryology,environmental and genetic
influences on normal growth and development, teratogenesis.
PRACTICAL
Models, specimens of early human development and slides of chick and pig embryos to correlate avian
and mammalian early development with human development. Specimens of congenital malformations.
IMMUNOLOGY
COURSE CONTENT
Immune system and the cell types involved in defense mechanisms of the body. Gross features,
cytoarchitecture, functions, development and histogenesis of various primary and secondary lymphoid
organs in the body. Biological and clinical significance of the major histocompatibility complex of man
including its role in transplantation, disease susceptibility/resistance and genetic control of the immune
response. Common techniques employed in cellular immunology and histocompatibility testing. Molecular
hybridization and PCR technology in immunology research particularly mechanism of antigen presentation,
structural and functional relevance of the T cell receptor, genetic control of the immune response,
molecular basis of susceptibility to disease.
PRACTICAL
Techniques of DNA preparation, electrophoresis and southern blot hybridization.
SECTION – 3
NEUROANATOMY
COURSE CONTENT
Brain and its environment, Development of the nervous system, Neuron and Neuroglia, Somatic sensory
system, Olfactory and optic pathways, Cochleovestibular and gustatory pathways, Motor pathways,
Central autonomic pathways, Hypothalamo-hypophyseal system, Cross sectional anatomy of brain and
spinal cord.
PRACTICAL
Identification of structures in sections of brain stem and spinal cord at different levels. Staining nervous
tissue using Nissl’s staining and other special stains.
RECOMMENDED BOOKS
1. Gray’s Anatomy 38th edition, 1995 reprint in 2000 Williams et al
Churchill Livingstone
2. Wheaters Functional Histology 4th ed.(2000) B. Young and J.Heath
Churchill Livingstone
3. Histology: A text & atlas 3rd edition (1995) M.H.Ross, E.& L.J.
Williams & Wilkins
4. Medical Embryology 8th edition Jan Langman
William and Wilkins
5. Genetics in medicine 6th edition, 2001 J.S.Thompson &
W.B. Saunders & Co.Philadelphia, London M.W. Thompson
6. Human Neuroanatomy 9th edition, 1996 Stuin J and Carpenter MB
7. Clinical Neuroanatomy for Medical Students Richard S. Snell
Willian and Wilkins
BIOCHEMISTRY — M Sc
Goal
The program is designed to enable a student acquire sound knowledge in the subject and develop
practical skills to contribute effectively in academics and health sciences research.
OBJECTIVES
1. At the end of the 2 years training in Biochemistry, the PG student is expected to demonstrate sound
knowledge of general concepts and principles of Biochemistry. Evolutionary perspectives of
biomolecules, cell organelles and diversity provided at the molecular level, discuss various aspects
of nutrition and metabolism under different physiological conditions, explain the occurrence, regulation
and interrelationship of metabolic events, identify the molecular/metabolic basis of a disease, explain
concepts of body defense/immunology and detoxification, molecular and cell biology, describe the
principles of various biochemical techniques and instrumentations and analyze and interpret the
data.
2. Plan & conduct lecture, practical demonstrations & tutorial classes.
3. Critically review & comment on research papers
4. Prepare research protocols to conduct experimental studies, analyse, interpret diseases, experimental
results of generate hypothesis.
5. Be familiar with literature survey / computer skills, basic knowledge of biostatistics.
METHODOLOGY
Following methods are used to facilitate learning and training of the students.
A. Theory
1. Tutorials: will be held for 1 hour duration, at least twice a month. The objective is to provide an
opportunity to the students to have interaction with the teachers and gain maximum coordinated
information on the subject.
2. Seminars: will be held once a month. The topics will be chosen from the latest advances in the
subject and also from areas of general biological / biochemical interest. One student will take up a
topic for one seminar, prepare and speak on it. Presentation and discussion will be for 1 hour. By
this exercise, the students will know the advanced developments in the fields & also learn, comprehend
and explain the information they have obtained.
3. Journal club: To develop a) skills of analysis, evaluation and presentation of research papers b)
familiarity with approaches and methodologies of research and c) to update on new development/
emerging trends in biochemistry.
4. Invited lectures: to gain access to recent work by an expert in an area and opportunity for free
interactions with scientists of eminence.
5. Relevant lectures in biotechnology
B. Practicals
Core- Biochemistry.
These will include some of the Biochemistry practicals from the undergraduate course.
Advanced practicals- Biochemistry, cell biology, molecular biology, immunology.
Some of the biochemistry practicals from the undergraduate course and from cell biology and immunology.
Students will attend this weekly biochemistry practicals. Other practicals will be arranged in the Deptt.
laboratories.
Advanced : Biochemistry, cell biology, molecular biology, immunology.
1. Study of the cell – (i) Cell culture, lymphocyte isolation & culture, growth rate studies, staining
techniques (ii) Cell fractionation, homogenization of the tissue, centrifugation, marker enzyme assays
(iii) Microscopy and microphotography.
2. Quantitative assays – (i) Enzyme assays (ii) RIA (iii) ELISA iv) DNA, RNA & proteins
3. Protein fractionation – (i) Salting in and out, gel filtration, electrophoretic separation (ii) Gel
filtration affinity based techniques (iii) SDS-PAGE (iv) Electrophoretic separation of LDH isoenzymes
4. Enzymology – purification of enzyme & its kinetics
5. DNA – (i) Genomic and plasmid DNA isolation (ii) Restriction enzyme digestion (iii) Electrophoresis
(iv) PCR (v) RT-PCR
6. Southern blotting
7. Western blotting
8. Tissue culture
9. Absorption & fluorescence spectroscopy
10. Chromatographic techniques – HPLC, Gel filtration, ion exchange, affinity chromatography
These practicals will give an exposure to the students on the basic techniques as well as advanced
techniques. A researcher uses in his/her studies.
Here is the attachment of syllabus of this exam: