What are the research areas of Cork Cancer Research Centre (CCRC), Ireland???
Answer:
Cork Cancer Research Centre major the issues in the development and treatment of cancer. Cork Cancer Research Centre (CCRC) provides a research partnership between the University and the teaching Hospitals.
Research Areas:
Cell Death and Survival Mechanisms
Drug Delivery Systems
Novel Therapeutics and Devices
Gene Therapy
Cancer Immunotherapy
List of Selected Publications:
-Electrochemotherapy for the treatment of ocular basal cell carcinoma; a novel adjunct in the disease management.
-Attentional Capacity: An Essential Aspect of Surgeon Performance.
-Bacterial-directed enzyme prodrug therapy.
-Use of optical imaging to progress novel therapeutics to the clinic.
-Review of current thermal ablation treatment for lung cancer and the potential of electrochemotherapy as a means for treatment of lung tumours.
-Pharmacological agents with inherent anti-autophagic activity improve the cytotoxicity of imatinib.
-Bacteria and tumours: causative agents or opportunistic inhabitants?
-Induction of autophagy by Imatinib sequesters Bcr-Abl in autophagosomes and down-regulates Bcr-Abl protein.
-Adenovirus-mediated transcriptional targeting of colorectal cancer and effects on treatment-resistant hypoxic cells.
-Bioluminescent bacterial imaging in vivo.
-DNA vaccination for prostate cancer, from preclinical to clinical trials – where we stand?
-Bacterial vectors for imaging and cancer gene therapy: a review.
-Objective structured assessment of technical skills and checklist scales reliability compared for high stakes assessments.
-Laparoscopic lavage for perforated diverticulitis: a population analysis.
-Control and augmentation of long-term plasmid transgene expression in vivo in murine muscle tissue and ex vivo in patient mesenchymal tissue.
-Prospective, randomized assessment of the acquisition, maintenance, and loss of laparoscopic skills.
-High resolution in vivo bioluminescent imaging for the study of bacterial tumour targeting.
-In vivo optical imaging in gene & cell therapy.
-The BH3 mimetic HA14-1 enhances 5-fluorouracil-induced autophagy and type II cell death in oesophageal cancer cells.
-Deficits in surgical technical performance: prolonged effects of alcohol.
Address:
Cork Cancer Research Centre
Leslie C. Quick Jnr. Laboratory
Biosciences Institute
University College Cork, Cork.
Ireland
Tel: +353 21 490 1437 W