#1
26th March 2016, 10:58 AM
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Synthesis Of Proteins
Hi buddy I am an science faculty student and making project on Synthesis Of Proteins and for the same I am looking for study material , so can you arrange some material for me ??
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#2
26th March 2016, 11:05 AM
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Re: Synthesis Of Proteins
As you said you are making project on Synthesis Of Proteins and for it looking for material , so for your help I am providing a pdf which having lotes of material related to same topics Here is some content from pdf Protein Synthesis Occurs by Initiation, Elongation, and Termination • The ribosome has three tRNAbinding sites. • An aminoacyltRNA enters the A site. • PeptidyltRNA is bound in the P site. • Deacylated tRNA exits via the E site. • An amino acid is added to the polypeptide chain by transferring the polypeptide from peptidyltRNA in the P site to aminoacyltRNA in the A site. Special Mechanisms Control the Accuracy of Protein Synthesis • The accuracy of protein synthesis is controlled by specific mechanisms at each stage. Initiation in Bacteria Needs 30S Subunits and Accessory Factors • Initiation of protein synthesis requires separate 30S and 50S ribosome subunits. • Initiation factors (IF1, 2, and 3), which bind to 30S subunits, are also required. • A 30S subunit carrying initiation factors binds to an initiation site on mRNA to form an initiation complex. • IF3 must be released to allow 50S subunits to join the 30SmRNA complex. A Special Initiator tRNA Starts the Polypeptide Chain • Protein synthesis starts with a methionine amino acid usually coded by AUG. • Different methionine tRNAs are involved in initiation and elongation. • The initiator tRNA has unique structural features that distinguish it from all other tRNAs. • The NH2 group of the methionine bound to bacterial initiator tRNA is formylated. Synthesis Of Proteins study material |
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