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9th December 2016, 09:23 AM
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Join Date: Aug 2012
Re: Syllabus For NIPPER

Ok, here I am providing you the syllabus of NIPER JEE Entrance Exam.

NIPER JEE Entrance Exam syllabus

Exam consists of 200 questions in 2 hours. (Please check it in Brochure).

200 mark paper
120 min. time

objective type paper (MCQ- multiple choice questions only)

Negative marking(0.25)/q..

Medicinal chemistry and Bulk Drugs (Pharmaceutical Technology)

IUPAC nomenclature, R and S nomenclature, E and Z isomerism, atropiisomerism, Conformations
Hybridization, aromaticity, Huckel’s rule reaction mechanisms- Electrophilic, Nucleophilic, SN1, SN2, SNi,
Elimination E1 E2 etc.
Ester hydrolysis, Aac1 Aac2……all eight mechanisms (Jerry march) Markovnikoves rule, Bredts rule,
Stereoselectivity, stereospecificity, regioselectivity, chemoselectivity, chirality, stereochemistry, conformations,
rearrangements, acids and bases.
Imine-enamine Tautomerism, keto-enol tautomerism, pericyclic reactions, racemic mixture, resolution methods.
Amino acids proteins, various methods for amino acid detection, Ninhydrin test, peptide sequencing, structures of
amino acids, essential and nonessential amino acids,
Introduction to thermal methods of analysis like, TGA, DSC, DTA etc.
Carbohydrates classification, osazone test, mutarotation, etc,
Various Heterocycles, Heterocycle synthesis, reactions.
Introduction to Redox reactions.
Spectroscopy: (basics specially): Very very IMP topic. NMR, and C-NMR ranges from Morrison & Boyd or Pavia
Mass -Basic concepts about various peaks M+1, molecular ion, base peak etc. (Silverstein) IR - Frequencies of
various groups specially carbonyls. UV
Reaction kinetics, first second third and pseudo first order reactions, radio labeling for determination of mechanism.
Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen etc.
Other reactions like Cannizarro’s reaction, Prins reaction, especially reactions of carbonyl compounds.
References:
1. Jerry March (Stereochemistry with special attention )
2. Morrison and Boyd (Do the Whole Book,ESPECIALLY Peptide and Carbohydrate chemistry)
3. I. L. Finar Vol-I and Vol-II (Heterocyclic chemistry and organic synthesis)
Spectral analysis (Most imp part)
1. UV & visible spectroscopy :
Basic principle, characteristic regions of spectrum, energy levels & selection rules,
woodward – fieser , fieser-kuhn & nelson rule. Influence of substituent, ring size & strain
on spectral characteristics, solvent effect, non-conjugated interaction ,spectral correlation
with structure , UV- values . (ref. Pavia )
2. Infrared spectroscopy:-
Characteristic regions of spectrum, influence of substituents, ring size, hydrogen bond,
vibrational coupling & field effect on frequency . Spectral interpretation, IR value.
(ref. Pavia )
3. Nuclear magnetic resonance spectrum:-
Magnetic nuclei, chemical shift & shielding, relaxation, processes, chemical &




For complete syllabus here is the attachment
Attached Files
File Type: pdf NIPER JEE Entrance Exam syllabus.pdf (64.3 KB, 576 views)


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