Mumbai University Biochemistry Syllabus

My brother get admission in M.Sc.( Biochemistry) course at Mumbai University . He want to get the syllabus of the 1st year course . will you please tell how he can download the syllabus of the M.Sc.( Biochemistry) 1st year course of Mumbai University.

Hi sir I am in the third year B.Sc. from Mumbai University I want to known about the syllabus of the subject Biochemistry please give me detail of it?

[Quick Sam]

Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms. By controlling information flow through biochemical signaling and the flow of chemical energy through metabolism, biochemical processes give rise to the complexity of life.

As you want to known about the syllabus of Biochemistry third year offered by Mumbai university

Here is the detail of it

Metabolism & Analytical Techniques-I

I Carbohydrate Metabolism
II Bioenergetics & Oxidative Phosphorylation
III Chromatography
IVpH and Buffers & Vitamins

Environmental Science
I Air
II Water & Water treatment
III Soil & Noise
IVEnergy, Industrial Pollutants and Environmental Monitoring

Advanced Genetics & RDT
I DNA Replication & Repair
II Transcription & Translation
III Recombinant DNA Technology (RDT)
IV RDT Recombinant DNA Technology (RDT) techniques

Immunology and Pathophysiology- I
I Human immune system
II Antigen- Antibody interactions
III Metabolic disorders, Blood related
diseases & Cardio Vascular System and related diseases
IV Cancer

Metabolism & Analytical Techniques-II
I Lipid metabolism
II Amino acid and protein metabolism & Endocrinology
III Centrifugation and Spectroscopy
IV Electrophoresis

Nutrition & Pharmacology
I Nutrition
II Diet Management
III Pharmacology
IV Mechanism of Drug Action and Therapeutic drugs

Biostatistics &Bioinformatics
I Biostatistics and descriptive statistics
II Probability & bioinformatics
III Hypothesis testing
IV Hypothesis testing

Immunology and Pathophysiology- II
I Antigen- Antibody interactions & Complement system
II Major histocompatibility complex &Transplant immunology
III Virology & AIDS
IV Endocrine Diseases & Ageing

Mumbai University Biochemistry Syllabus
T.Y.B.Sc. – BIOCHEMISTRY ( 6 units )
METABOLISM & ANALYTICAL TECHNIQUES-II
I 1.0 Lipid metabolism 15
1.1 Lipid metabolism – ,
Catabolism - Knoop’s experiment ; Beta oxidation of even
carbon saturated fatty acids ( C4 to C20 ) Energetics of fatty
acid oxidation .
1.2 Anabolism – Fatty acid biosynthesis (palmitic acid) ,
Ketone body formation, utilization, and the physiological
significance of Ketone bodies in Diabetes mellitus, Starvation,
Pregnancy and Alcoholism.
II 2.0 Amino acid and protein metabolism & Endocrinology 15
2.1 Amino acid and protein metabolism –
Reactions of amino acids – Transamination [GOT/GPT and
mechanism of transamination] ; Decarboxylation [ His, Trp,
Glu, and mechanism of decarboxylation ] , Deamination [
oxidative – NAD(P) linked dehydrogenases and D & L -
Amino acid oxidases, Non oxidative – Asp, Cys, Ser ]
2.1.2 Urea cycle – Cellular location, sequence of reactions, Labeling
of N atom, transport of NH3
2.2
2.2.1
Endocrinology
Chemistry, synthesis , secretion and physiological effects of
Thyroxine and Insulin [synthesis from preproinsulin],
Diabetes mellitus , Hypothyroidism [cretinism and
myxedema], Hyperthyroidism [goiter – simple & toxic ]
Physiological role of Glucocorticoids, Oxytocin and ADH
2.2.2 Mode of action of steroid hormones, Effect of epinephrine on
glycogen synthesis and breakdown [amplification cascade with
G proteins, cAMP, adenylate cyclase, kinases]
III 3.0 Centrifugation and Spectroscopy 15
3. 1
3.1.1
3.1.2
3.1.3
Centrifugation
RCF , RPM and derivation of an equation relating the two ;
Nomogram ; Sedimentation coefficient
Types and applications of centrifuges – Clinical, High speed,
Ultra centrifuge - preparative and analytical.
Types of centrifugation and its applications– Differential, Rate
zonal, Isopycnic ( Centrifugation with and without density
gradients)
3.2
3.2.1.
3.2.2
3.2.3
Spectroscopy :
Beer-Lambert law, derivation , limitations, application –
estimation of sugar(DNSA) and protein(Biuret); concepts of
Lambda max; determination of molar extinction coefficient
Construction and working of a simple colorimeter and
spectrophotometer
Applications of Beer-Lambert law in the estimation of
sugar[DNSA] and protein[Biuret]
3.2.4 Numericals based on the above concepts
IV 4.0 Electrophoresis 15
4.1
4.2
4.3
4.4
Principle ; Factors affecting the rate of migration of sample in
an electric field
Supporting media – paper, cellulose acetate, agar, agarose and
polyacrylamide
Discontinuous electrophoresis – Native PAGE
Applications of electrophoresis - Separation of proteins and
Nucleic acids with one staining method for each; molecular
weight determination
NUTRITION & PHARMACOLOGY
I 1.0 Nutrition 15
1.1
1.1.1
1.1.2
1.1.3
Principles of nutrition
Nutrients [Proximate principles, vitamins and minerals( macro
and micro- role of Ca, Mg, Na, K and Fe, Zn)] , dietary fibre.
Nutritional status [malnutrition ( protein energy and protein
calorie) and over nutrition]
Balanced diet
1.2.1
1.2.2
1.2.3
Energy Assessment - RQ, BMR ;
Anthropometry – BMI, Waist:hip ratio ;
Protein quality indices : Chemical score of amino acids,
Protein Deficiency Corrected Amino Acid Score, Net Protein
utilization
II 2.0 Diet Management 15
2.1 Dietary Management in :- Obesity, Diabetes Mellitus,
Hypertension, Peptic ulcer , Obstructive Jaundice
III 3.0 Pharmacology 15
3.1
3.1.1
3.1.2
3.1.3
3.1.4
General pharmacology
Pharmacodynamics, Physicochemical properties of drugs,
Drug absorption : through-GIT, pulmonary, renal, placental
and blood-brain barrier
Bioavailability and Bioequivalence
Drug Distribution, Metabolism and Excretion
3.2 Bioassays : Preclinical and clinical evaluation,
Therapeutic drug monitoring
3.3 Pharmacokinetics :
LD50, ED50, Half Life , Loading dose, Maintenance dose,
Therapeutic dose, Therapeutic Index,
Drug plasma concentration, Volume of distribution, Clearance
IV 4.0 Mechanism of Drug Action and Therapeutic drugs 15
4.1
Mechanism of action of drugs :
i. Specific interaction – receptor mediated
ii. Partially specific – drugs via enzymes

For more detail about the syllabus of Biochemistry Mumbai universitygo through this PDF;