Model Papers for JNU MSc Biotech Entrance

Will you please provide me question paper for Jawaharlal Nehru University MSc Biotech Entrance examination soon ?

[Kiran Chandar]

Here I am giving you question paper for Jawaharlal Nehru University MSc Biotech Entrance examination in a file attached with it so you can get it easily.
1 . A haploid human
(a) 3xloe bp
(b) 2xtoe bp
(c) 6xtoe bp
(d) 9xloe bp
PART-A
genome would have
2. pH of an aqueous solution is 4. What is its pOH?
(a) 4
(b) 3
(c) 10
(d) 12
Non-pigmented bacterial suspensions also show optical density in visible light, becduse
of
(a) absorption of light of specific wavelength
(b) refraction of specific wavelengths of light
(c) non-specific refraction of light
(d) scattering of light
The counts of bacteria per mL in samples withdrawn at two time points separated by
one hour in the exponential phase are ca 1.5x 108 and 6x 108, respectively. The
generation time of the bacterium should be
(a) I hour
(b) 4 hours
(c) j trour
(d) { hour
For precipitating DNA from a solution in saline aqueous medium, it is recommended to
add 2 volumes of absolute ethanol. The final concentration of ethanol in precipitating
medium would be
(a) 33o/o (v/v)
(b) 33o/o (w/vl
(c) 660/o (v/v)
(d) 66% (wlvl

6. A restriction enzyrne recognizes four contiguous base pairs in DNA. What will be the
approximate frequency of its occurrence?
(a) Once in 300 bp
(b) Once in 3 kb
(c) Once in 10 kb
(d) Once in 100 kb
The primary hosts for HIV-I virus are
(a) monoc5rtes
(b) T4 helper cells
(c) T8 killer/suppressor cells
(d) B cells
A father's age is the sum of the ages of his three sons. If the ratio of the ages of the sons
is 1 : 2 : 3 and eight years later the difference between the ages of the father and the
youngest son is 35 years, what is the current age of the eldest son?
(a) 30 years
(b) 28 years
(c) 21 years
(d) 24 yeats
Carbon atoms in graphite are in
(a) sp2 configuration
(b) sp3 configuration
(c) unbound form
(d) There are triple bonds between carbon atoms
The age of the universe is estimated to be
(a) 4.5 billion years
(b) 13. 5 billion years
(c) 200 billion years
(d) 3. 5 billion years

1 1 . Human existence on the earth can be traced back to
(a) less than 10000 years
(b) 10000 to 100000 years
(c) 1 million to l0 million years
(d) 10 million to 100 million years
Which of the following transformations is an oxidation?
(a) voJ -+ voi
(b) cro! -+ crol-
(c) so! -+ so!-
(d) No! +Nol
How many different compounds have the formula CuHrO ?
(a) One
(b) TWo
(c) Three
(d) Four
Which of the following salts is colourless?
(a) KMnOo
(b) BaSOo
(c) NarCrOo
(d) CuSOo
Which of the following molecules contains the. sho;test carbon-carbon bonds?
(a) CzHz
(b) czH+
(c) CaHa
(d) coHtz

16. Gregor Johann Mendel's experirnents with garden peas established that
(a) inheritance of characters is mediated by DNA
(b) there is a quantitative pattern of inheritance traits that correlate with the traits of
paxents. This suggests for some material basis of inheritance
(c) those are the chromosomes that are passed on to next generation
(d) the nature of genetic material is acidic
t7. The unit of organization and functioning of living systems is
(a) cell
(b) nucleus
(c) plasma membrane
(d) mitochondria
18. The non-covalent bonds in biological system have a free energr in which of the following
ranges?
(a) 0. I kcal/mole
(b) 1-7 kcal/mole
(c) > l0 kcal
(d) No range of free eners/ can be defined for weak interactions
19. How many decapeptide variants will result if during peptide synthesis, ten of the twent5r
amino acids are allowed to be incorporated randomly?
(a) 1o2o
(b) lor '
(c) loro
(d) 2OLo
20.. The pressure of 14'7 pounds per square inch is equivalent to
(a) I atmosphere
(b) 2 atmosphere
(c) 5 atmosphere
(d) 1O atmosphere
6 /3-A
2L, Nitrogen liquefies at
(a) - 196 K
(b) - 196'C
(c) 77 "F
(d) -273 K
22. Which of the following const_ituents. is present in.viruses?
(a) Protein synthesis platform (ribosomes)
(b) Enzyme system for energr metabolism
(c) Mitochondria
(d) Genetic material
23. In an ecosystem, at which trophic lqvel is the biomass maximal?
(a) Primary producers
(b) Herbivorousconsumers
(c) Carnivorous consumers
(d) Decomposers
24. Which of the following cellular organisms has been revived by putting a synthetic
genome in ghost cells?
(a) Mgcobacteium smegmati.s
(b) Mgcobacteium tuberculosis
(c) Mgcoplasma genitalium
(d) Escherichia coli
25, Who among the following scientists was responsible for adopting X-rays for clinical
imaging?
(a) Ernest Rutherford
(b) Niels Bohr
(c) Marie Curie
(d) Wilhelm Roentgen

26, If log" 9 =2, then x =
(a) 4 . s
(b) 18
(c) 3
(d) 2
27. Which of the following amino acids contains sulfur?
(a) Alanine
(b) Glutamine
(c) Tryptophan
(d) Cysteine
24. As brakes are applied in a car, books on the passenger seat suddenly fly forward. That
is most likely, because
(a) the car is not an inertial reference frame
(b) the seat supplies a forward push to make the books accelerate
(c) there is a strong gravitational field generated by the brakes
(d) there is a strong magnetic field generated by the brakes
29, Zero kelvin is defined as the temperature at which
(a) ice coexists with seawater at 1 atm
(b) ice coexists with pure water at 1 atm
(c) steam coexists with pure water at 1 atm
(d) one mole of argon gas would exert zero pressure
30. What is the oxidation number of manganese in KMnOo?
(a) 3
(b) s
(c) 7
(d) e

31. Which of the following is closest to the number of different sequences in a pool of
random sequence 25-mer oligonucleotide?
(a) lor2
(b) lors
(c) 1o2o
(d) ro25
32. In a four-point (ABCD) cross between Hfr and F- strains of E. coli, the pair-wise
frequencies of recombination fell in the following order :
rhe most probable order
"r.n":.";::::r"cterial
chromosome would be
(a) ABCD
(b) ACDB
(c) ADCB
(d) ABDC
33. In the Holliday model of DNA recombination, branch migration is mediated by
(a) Ruv A and Ruv B
(b) Ruv A and Ruv C
(c) Ruv B and Ruv C
(d) Ruv A alone
34. At low titres, adsorption of virions by host cells follows a Poisson distribution. If a
suspension of 106 virions is added to lO6 host cells, the number of cells that will
receive at least one virus particle would be close to
(a) 3.7 x l o s
(b) 6.3 x los
( c ) 3 . 7 x 1 0 6
(d) 6.3 x 106

35. A genetic signature is created, based on'6unlinked markers (a-f) with the frequeacies
(a) O'01, (b) 0'02, (c) 0'003, (d) 0'001, (e) O'OOa and (f) 0'05. The theoretical probability of
two individuals sharing this signature is
(a) L.2 x lo-r2
(b) 1.2 x 1o-r3
(c) 1.2 x 1o-11
(d) 7.2 x Lo-6
36. Embryonic cleavage in most of the teleost frshes is
(a) holoblastic
(b) semi-holoblastic
(c) meroblastic
(d) All of the above
37. Placental connection is typical of
(a) viviparousreproduction
(b) ovoviviparousreproduction
(c) oviparous reproduction
(d) All of the above
38. The optic lobe is also referred to as
(a) cerebellum
(b) tegmentum
(c) tectum
(d) pons


39. Larvae of the crab genus Carcinus swim towards the water surface when pressut-e
increases. This is an example of
(a) photokinesis
(b) thigmokinesis
(c) barokinesis
(d) orthokinesis
40. Ciliary wheel organ used for locomotion is typical of
(a) molluscs
(b) sponges
(c) rotifers
(d) Animals do not have wheels
4L. Retting is biodegradation of
(a) cellulose
(b) lignin
(c) pectin
(d) retinol
42. The value of which of the following parameters is zero when the cell is fully tur$d?
(a) Turgor pressure
(b) Wall pressure
(c) Osmotic pressure
(d) Diffusion pressure deficit

43. The edible partf black pepper is
(a) aril
(b) perisperm
(c) embryo
(d) cotyledon
44. The advanced character in Cucurbitaceae is
(a) inferior ovary
(b) pepo fruit
(c) tendril
(d) parietalplacentation
45. Krattz anatomv is seen in
(a) all monocots
(b) monocots with C4 pathway
(c) monocots and dicots with Co pathway
(d) legumes
46. The nurnber of pyrrole rings included in a porphyrin is
(a) three
(b) four
(c) five
(d) six


47. Among the E. colt DNA polymerases, which of the following haq. a 5',i.3' gxonuclease
activity?
(a) Pol5rmerase I
(b) Pol5rmerase II
(c) Polymerase III
(d) Polymerase e
44. Which of the following amino acids is found both'in and L forrns in peptidoglycan? '
(a) Alanine
(b) Glutamic acid
(c) Glutamine
(d) Lysine
49. Which one of the following enzymes in mammalian cells is attached to ttrg membrane by
a GPl-anchor?
(a) Alkalinephosphatase
(b) Lysyl oxidase
(c). NADPH-cytochrome P-450 reductase
(d) Adenylate cyclase
50. Cell surface protein that is .not present in. a B cell,is
,(a) cD4
(b) cD8
(c) cD3
(d) All of the above

51. Smallpox virus genome is a
(a) single-strandedDNA
(b) double-stranded linear DNA
(c) single-stranded RNA (+strand)
(d) single-stranded RNA (-strand)
52. The nucleic acid base with no oygen in its molecule is
(a) adenine
(b) c5rtosine
(c) guanine
(d) thymine
53. Which of the following operons is regulated by both repression and attenuation?
(a) Arabinose operon
(b) Histidine operon
(c) Tryptophan operon
(d) p-Galactosidaseoperon
54. Which of the following is closest to the size of a white blosd-cell?
(a) 1 mm
(b) 0. 5 mm
(c) 0.05 mm
(d) O.Ol mm

Transposons (jumping genes) were discovered by
(a) Temin
(b) Abelson
(c) Harvey
(d) McClintock
56. SDS-PAGE separates proteins mainly on the basis of mass and not charge, because
(a) SDS neutralizes the proteins to be separated
(b) neutral species can move in electrical field only on the basis of mass
(c) SDS confers homogeneous negative charge on the protein molecules
(d) B-mercaptoethanol neutralizes the protein molecules
57. Southern blotting detects
(a) DNA
(b) RNA
(c) proteins
(d) carbohydrates
58. Which of the following subunits of E. coli RNA polymerase is essential for promoter
recognition?
(a) Alpha
(b) Beta
(c) Beta'
(d) Sigma

59. Which of the following membranes'has the greatest ratio of lipid to protein?
(a) Mitochondrial inner membrane
(b) Myelin
(c) Sarcoplasmic reticulum
(d) Membrane of the Golgi bodY
60. Inhibition of HMG-CoA reductase decreases the rate of synthesis of
(a) acetoacetate
(b) cholesterol
(c) palmitate
(d) phosphatidic acid
61. Biosynthesis of proline employs which of the following precursors?
(a) Alanine
(b) Glycine
(c) ,{spartic acid
(d) Glutamic acid
. ' '
62. Lyme disease is caused by the bacterium
(a) Clostridium tetani
(b) Pseudomonns aentginosa
(c) Borrelia burgdorferi
(d) Bordetellnperfnsstis

63. The haemoglobin chain that replaces the beta chain in embryonic haemoglobin is
(a) delta
(b) epsilon
(c) gamma
(d) alpha
64, The codon found to ertcode sehenocysbine: is'
^ (a) UAA
(b) UAG
(c) UGA
(d) uAc
65. The oncogene that was ldentified frrst is '
(a) Mas
(b) Myc
(c) Src
(d) sip
66. Vitamin 812 Fobalamin) i$ only'synthesiured by
(a) fishes
(b) microorganisms
(c) plants
(d) mammals

67, Chlorophyll molecules in chloroplasts are located in
(4 stroma
(b) thylakoid
(c) internal lipid micelle
(d) inner chloroplast membrane
68. In addition to AUG, what initiation codon is reeognized by prokaryotes? : ,
(a) AcG
(b) cuc
(c) GUG
(d) AAG
69. The dye used in Gram's staining protocol'for baeteria is
(a) eosin
(b) hematorylin
(c) iodine and crystal violet
(d) methylene blue
7o. Which of the following bacterial protein toxins is tlre most potent toxin?
(a) Botulin
(b) Diphtheria toxin
(c) Tetanus toxin
(d) Cholera toxin

7L. The bases that can pair with inosine (in tRNA) according to the wobble hypothesis fre
(a) A, C and G
(b) A, C and U
(c) C, G and U
(d) A, G and U
72. The number of chromosomes in the budding yeast (Saccharomgces cereuislae) is
(a) 16
(b) 17
(c) 18
(d) I
73. Fc and Fab fragments of IgG are produced upon digestion with
(a) chymotrypsin
(b) papain
(c) trypsin
(d) lysozyme
74. The activity of transaminase is dependent on the coenzyme
(a) biotin
(b) pyridoxalphosphate
(c) tetrahydrobiopterin
(d) albumin

75. .Which one'of the following is riot a plant horrnone?
(a) Indoleacetic acid
(b) Gibberellic acid
(c) Prephenate
(d) Zeatin
76. ' -edtabolie' bredkdown of ala.nine yrelds
(a) fumarate
(b) oxaloacetate
(c) pynrvate
(d) rnalate
77. Which of the ftllit!9{ng irirtrses replicat€s in the cytbplasm?
(a) Epstein-Barr virus
(b) Poliovirus
(c) Vaccinia
(d) Papillomavirus
7E. Plant leghaemoglobin in:root nodules provides oxygen to t*re
(a) roots
(b) amyloplasts
(c) bacteroids
(d) chloroplasts

79. Retroviral replication is prirneil by
(a) a short linear RNA
(b) a tRNA
(c) a viral protein
(d) a ribosomal RNA
80. Bv which year were all the triplet codons defined?
(a) r9s2
(b) 1es8
(c) 1966
(d) 1e68
81. The lanibda'phage's represdot piotein.binds' tb"DilIA aS a
(a) dimer
(b) monomer
(c) trimer
(d) tetramer
a2. The lirst recessive'gClreticdisorder dSicribed'tdas : ' r:":' -i
(a) albinism
(b) alkaptonuria
(c) phenylketonuria
(d) sickle-cellanaemia

83. The selection markers on the plasmid pbr322 confer resistance to
(a) chloramphenicol and kanamycin
(b) kanamycin and ampicillin
(c) kanamycin and tetracycline
(d) tetracycline and ampicillin
84. Ribotyping is
(a) 55 rRNA based
(b) 165 rRNA based
(c) 23S rRNA based
(d) None of the above
85. In protein structure, the cr-helix and B=pleated sheets are examples of
(a) primary structure
(b) secondarystructure
(c) tertiary structure
(d) quatemary structure
86. Genetic engineering requires which of the following enzymes?
(a) B-Galactosidase
(b) Amylase
(c) Lipase
(d) Restrictionendonuclease

87. The minimum size of an epitope is
(a) one amino acid residue
(b) two amino acid residues
(c) five amino acid residues
(d) twenty amino acid residues
88. Plastics do not elicit good antibody response, because
(a) they are toxic
(b) they are hydrophobic
(c) they are artificially synthesized
(d) they cannot be processed and presented as antigens
89. An autoimmune disease is caused by
(a) defective thymus development
(b) defective cellular immunity
(c) defective bone marrow
(d) immune response against self-antigens
90. Which of the following drugs is used for immunocompromising patients receiving
grafts?
(a) Streptomycin
(b) Cyclosporine
(c) Tetracycline
(d) Penicillin

91. Suppose the density of a solid is D and its average atomic r-nass is M. Which of thp
following represents the average spacing between the atoms in the solid?
(a) D/M
(b) M /D
(c) (D /uflz
(d) (M /n1r/s
92. A person A is in an elevator. Another person B, sitting on the ground, observes A to be
travelling upward with a constant speed of 5 m/s. At one instant, A drops a pen from i
rest. Immediately after, the acceleration of the pen according to A is
(a) 10 m /s2, down
(b) 0
(c) 15m/s2, down
(d) 5m/s2, up
93. A mass hangs from an ideal spring. When the mass is set into oscillation with
amplitude of I cm, its frequency is 1O Hz.lf the amplitude is increased to 2 cm, the new
frequency will be
(a) 5 Hz
(b) 7 Hz
(c) LO Hz
(d) 2o Hz
94. ,Ttvo artificial bones.{solid cylindrical) are made of the same rnaterial and length; one
with twice the radius as the other. When the two have the same tension force applied,
the larger bone stretches by what factor compared to the smaller bone?
(a) 2
(b) o.2s
(c) 0 . 5
(d) 4

95. Ttvo identical blocks of mass m are tied together (by a light cord) and pulled up a rough
inclined plane at constant speed by a pulling force F directed along the incline and
applied to the upper block. Which of the following statements is true?
(a) The work done by F is zero because the blocks move at constant speed
(b) The total friction force must equal F because the blocks move at constant speed
(c) The tension in the cord is F because dhe two blocks are identical
(d) The work done by F is equal in magnitude to the work done by gravity plus the
work done by friction
96. In a head-on collision between a bird and a jet airplane
(a) the momentum of the airplane is exactly conserved
(b) the total kinetic enerry is exactly conserved
(c) the magnitude of the change in momentum of the bird divided by the collision time
equals the magnitude of the average force on the jet
(d) the total momentum is zero
97. A damped driven oscillator has €ur equation of motion given by
rrtn = - loc - bu + Fo cos (oo t), where oo is the angular frequency of the driving force.
At resonance, ma must be equal to
(a) - li.lc
(b) - bu
(c) + .{o cos (roo t)
(d) zero
98. ultrasonic imaging (ultrasonography/ultrasound) is not based on
(a) pulse-echo techniques
(b) differences in acoustic impedance
(c) cavitation
(d) scanning

gg. The equipotential surfaces around a long straight wire with a uniform charge/length
are concentric
(a) spheres
(b) cylinders
(c) triangles
(d) planes
1OO. "The current in a resistor is directly proportional to the potential difference across the
resistor." It is known as
(a) Coulomb's law
(b) Gauss's law
(c) Ohm's law
(d) Ampere's law
1O1. If the first-order double-slit diffraction minimum lies at the same place as the
fourth-order interference maximum, how many fringes will be visible in the central
diffraction maximum?
(a) 3
(b) s
(c) 6
(d) 7