Delhi University Zoology

Hello Sir I have done B.Sc and now I want to pursue M.Sc (Zoology) from Delhi University. Please tell me what is the Admission Criteria for this Programme? Kindly provide me list of all the Faculty members in Department of Zoology so I will get idea about its Educational Quality.

Can you provide me the syllabus/course structure of M.Sc (Master in Science) Zoology program offered by Department of Zoology, University of Delhi?

[pawan]

The syllabus/course structure of M.Sc (Master in Science) Zoology program offered by Department of Zoology, University of Delhi is as follows:

ZOOL 101: Genetics and Cytogenetics
Theory
Mendels laws and their chromosomal basis; extension of Mendels principles: allelic variation and gene function- incomplete dominance and co-dominance, allelic series, testing gene mutations for allelism; gene action- from genotype to phenotype penetrance and expressivity, gene interaction, epistasis, pleiotropy; nature of the gene and its functions: evolution of the concept of the gene, fine structure of gene (rII locus); methods of gene mapping: 3- point test cross in Drosophila, gene mapping in humans by linkage analysis in pedigrees.
Gene mutation and DNA repair: types of gene mutations, methods for detection of induced mutations, P- element insertional mutagenesis in Drosophila, DNA damage and repair; regulation of gene activity in lac and trp operons of E. coli, general introduction to gene regulation in eukaryotes at transcriptional and posttranscriptional levels, organization of a typical eukaryotic gene, transcription factors, enhancers and silencers, non coding genes.
Sex determination and dosage compensation: sex determination- in humans, Drosophila and other animals; dosage compensation of X-linked genes hyperactivation of X-linked gene in male Drosophila, inactivation of X-linked genes in female mammals; human genetics- karyotype and nomenclature of metaphase chromosome bands; chromosome anomalies and diseases- chromosomal anomalies in malignancy (chronic myeloid leukemia, Burkitts lymphoma, retinoblastoma and Wilms tumor); genetic analysis of complex traits - complex pattern of inheritance, quantitative traits, threshold traits; human genome and mapping.
Genetics and cancer: oncogenes- tumor inducing retroviruses and viral oncogenes; chromosome rearrangement and cancer; tumor suppressor genes- cellular roles of tumor suppressor genes, pRB, p53, pAPC, genetic pathways to cancer.


Suggested Literature:
1. Principles of Genetics, Snustad and Simmons, (4th Ed. 2005), John Wiley & Sons, USA
2. Modern Genetic Analysis: Integrating Genes and Genomes, Griffiths, J.F., Gelbart, M., Lewontin, C. and Miller, W. H. Freeman and Company , New York, USA
3. Genetics, J. Russell, Benjamin-Cummings Publishing Company, San Francisco, California, USA

ZOOL 101: Genetics and Cytogenetics


Practical

1. Study of mutant phenotypes of Drosophila.

2. Demonstration of law of segregation using Drosophila mutants.

3. Study of law of independent assortment.

4. Demonstration of sex- linkage by using white mutation of Drosophila.

5. Demonstration of dosage compensation in Drosophila males and females.

6. Demonstration of Green Fluorescence and Red Fluorescence protein for
monitoring gene expression.

7. Targeted tissue specific expression of a gene using UAS-Gal4 System in
Drosophila.

8. Preparation and study of metaphase chromosomes from mouse bone
marrow:

a. Chromosome banding (C, G, H banding).

b. Study the differences in number, shape and size of chromosomes in
normal vs. tumor cells, or normal vs. irradiated cells.

c. Preparation of human karyotype and study of chromosomal aberrations
with respect to number, translocation, deletion etc. from the pictures
provided.

9. Study of transcriptional activity in polytene chromosome upon heat shock
induction by uridine incorporation.

10. Study of sex chromatin in buccal smear and hair bud cells (Human).

11. Study of Hardy Weinberg equilibrium in human population by taking the
example of blood group system (ABO).