Ddu dundee

I want to know some information related to Drug Discovery Unit University of Dundee, so will you please provide here Drug Discovery Unit University of Dundee details???

[Quick Sam]

Drug Discovery Unit University of Dundee is a fully operational, fully integrated drug discovery group working across multiple disease areas.

Capabilities

Drug Metabolism and Pharmacokinetics
Integrated DMPK group
Supports hit and lead optimisation programmes
Industry standard in vitro and in vivo assays
State-of-the-art UPLC-MS/MS

Hit Discovery
Comprehensive range of liquid handling and detector technologies, including nanolitre acoustic dispensing
Protein and cell-based screening
High content images
Fragment-based screenings: SPR, NMR and Octet RED284
Industry standard data management - ActivityBase, Dotmatics

Medicinal Chemistry
Hit validation to lead optimisation
Parallel chemistry
Mass directed auto-prep HPLC purification
Structural Biology & Biophysical Techniques
State-of-the-art protein crystallography infrastructure
SPR: hit validation and determining enzyme kinetics

Bioinformatics
Statistics, computational science, databases, algorithms
Management and analysis of biological data
Mapping, analysing and aligning DNA and protein sequences
Building 3D models of protein structures

Computational Drug Design
Druggability assessment of molecular targets
Library selection
Virtual screening
Analysis of hits from screening
Pharmacophore searching
Compound design using protein structures
In silico ADMET optimisation

Management Team
Professor Paul Wyatt FRSE
Professor Ian Gilbert
Dr David Gray
Dr Kevin Read
Dr Andrew Woodland
Dr Julie Brady
Louise Burns
Professor Mike Ferguson
Professor Alan Fairlamb

Contact:
Drug Discovery Unit
College of Life Sciences
University of Dundee
Dow Street
Dundee DD1 5EH

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