AIIMS Entrance Exam eligibility Criteria and Form availability date

I am looking to take admission in MBBS at AIIMS so I want to know about AIIMS Entrance Exam eligibility Criteria and Form availability date

[Arun Vats]

The AIIMS MBBS Entrance Exam is conducted by All India Institute of Medical Sciences for admission to MBBS course. Here I am giving you important dates for admission in MBBS course offered by All India Institute of Medical Sciences

Important dates:
Starting date of Online Registration- First week of March 2014
Last Date of Online registration-24th March 2014
Admit Card announcement Date-16th May 2014
AIIMS MBBS Exam Date-01st June 2014
AIIMS MBBS Result Declaration Date-01st July 2014

Now dates for AIIMSD MBBS entrance exam is over, next year exam notice will publish in march month of 2015 year .

Eligibility :
You must Pass 12th Standard with physics, chemistry and biology subject and obtained a minimum 60% marks (50% for SC/ST candidates) from any recognize

Application fees:
Application fee for AIIMS UG 2014 entrance exam is:
Rs 1000 for General/ OBC category
Rs 800/- for SC/ST category

Entrance Test Cut Off
Category Minimum Cut-Off Marks
General including OPH belonging to General Category 50%
OBC including OPH belonging to OBC Category 45%
SC/ST including OPH belonging to SC/ST Category 40%

AIIMS Syllabus covers following topics
Anatomy
Biochemistry
Physiology
Forensic Medicine & Toxicology
Microbiology
Pathology
Pharmacology
Anaesthesiology
Community Medicine
Dermatology & Venereology
Medicine
Obstetrics & Gynaecology
Ophthalmology
Orthopaedics
Otorhinolaryngology
Paediatric
Psychiatry
Surgery
Internship

AIIMS Entrance Exam Syllabus

PHYSICS
Unit : 1 Introduction and Measurement.
Unit : 2 Description of Motion in One Dimension.
Unit : 3 Description of Motion in Two and Three Dimensions.
Unit : 4 Laws of Motion.
Unit : 5 Work, Energy and Power.
Unit : 6 Rotational Motion.
Unit : 7 Gravitation.
Unit : 8 Heat and Thermodynamics.
Unit : 9 Oscillations.
Unit : 10 Waves.
Unit : 11 Electrostatics.
Unit : 12 Current Electricity.
Unit : 13 Thermal and Chemical Effects of Currents.
Unit : 14 Magnetic Effect of Currents.
Unit : 15 Magnetism.
Unit : 16 Electromagnetic Induction and Alternating Currents.
Unit : 17 Electromagnetic Waves (Qualitative Treatment).
Unit : 18 Ray Optics and Optical Instruments.
Unit : 19 Electrons and Photons.
Unit : 20 Atoms, Molecules and Nuclei.
Unit : 21 Solids and Semiconductor Devices.

Crystal structure-Unit cell; single, poly and liquid crystal (concepts only).

CHEMISTRY
Unit : 1 Some basic concepts in Chemistry.
Unit : 2 States of matter.
Unit : 3 Atomic structure.
Unit : 4 Classification of elements and periodicity in properties.
Unit : 5 Chemical energetic.
Unit : 6 Chemical bonding.
Unit : 7 Equilibrium Equilibrium in physical and chemical processes Ionic equilibrium.
Unit : 8 Redox reactions.
Unit : 9 Solid state Chemistry.
Unit : 10 Chemical thermodynamics.
Unit : 11 Solutions.
Unit : 12 Chemical kinetics.
Unit : 13 Electrochemistry.
Unit : 14 Surface chemistry.
Unit : 15 Hydrogen.
Unit : 16 s-Block Elements (Alkali and Alkaline Earth metals).
Unit : 17 General principles and processes of isolation of elements.
Unit : 18 p-Block Elements.
Unit : 19 The d-and f-Block elements.
Unit : 20 Coordination compounds.
Unit : 21 Some basic principles of Organic Chemistry.
Unit : 22 Hydrocarbons.
Unit : 23 Purification and characterization of carbon compounds.
Unit : 24 Organic compounds with functional groups containing halogens (X).
Unit : 25 Organic compounds with functional groups containing oxygen.
Unit : 26 Organic Compounds with functional group containing nitrogen.
Unit : 27 Polymers.
Unit : 28 Environmental Chemistry.
Unit : 29 Biomolecules.
Unit : 30 Chemistry in everyday life.

BIOLOGY (BOTANY & ZOOLOGY)
Unit : 1 Diversity in Living World.
Unit : 2 Cell : The Unit of Life; Structure and Function.
Unit : 3 Genetics and Evolution.
Unit : 4 Structure and Function – Plants.
Unit : 5 Structure and Function - Animals.
Unit : 6 Reproduction, Growth and Movement in Plants.
Unit : 7 Reproduction and Development in Humans.
Unit : 8 Ecology and Environment.
Unit : 9 Biology and Human Welfare.
Unit : 10 Biotechnology and its Applications.

BIOCHEMISTRY
OBJECTIVES
Knowledge
At the end of the course, the student should be able to: demonstrate his knowledge and understanding on
the:
1. Molecular and functional organization of a cell, and sub- cellular components;
2. Structure, function and interrelationship of biomolecules and consequences of deviation from normal;
3. Basic and clinical aspects of enzymology and regulation of enzymatic activity;
4. Digestion and assimilation of nutrients and consequences of malnutrition;
5. Integration of the various aspects of metabolism, and their regulatory pathways;
6. Biochemical basis of inherited disorders and their associated sequelae;
7. Mechanisms involved in maintenance of body fluid and pH homeostasis;
8. Molecular mechanisms of gene expression and regulation, the principles of genetic engineering and
their application in medicine;
9. Molecular concepts of body defence and their application in medicine;
10. Biochemical basis of environmental health hazards; and biochemical basis of cancer and
carcinogenesis, principles of metabolism, and detoxication of xenobiotics.
11. Principles of various conventional and specialized laboratory investigations and instrumentation,
analysis and interpretation of a given data; the ability to suggest experiments to support theoretical
concepts and clinical diagnosis.

Skills
At the end of the course, the student should be able to
1. make use of conventional techniques/ instruments to perform biochemical analysis relevant to clinical
screening and diagnosis

2. analyze and interpret investigative data
3. demonstrate the skills of solving clinical problems and decision making.

COURSE CONTENT
Theory
Biological cell
(a) Architecture, compartmentation, cell membrane structure and functions; structure- function
relationships.
(b) Membrane transport.

Biomolecules
(a) Function and classification of carbohydrates, lipids, protein and amino acids.
(b) Stereoisomerism and chemistry of monosaccharides, amino acids, and fatty acids.
(c) Structural organization and structure-function relationships of proteins. Hemoglobin and myoglobin,
molecular mechanism of O2 transport and storage. Molecular basis of sickle cell anaemia and
thallesemias.
(d) Molecular mechanism of muscle contraction.
(e) Plasma proteins, their functions and clinical significance.

Enzymes
(a) Nomenclature, classification,
(b) Kinetics, mechanism of enzymatic catalysis.
(c) Factors influencing enzymatic catalyses, enzyme activators and inhibitors.
(d) Regulation of enzyme activity,
(e) Clinical enzymology, isoenzymes.

Metabolic pathways, their regulation and metabolic interrelationships
Metabolism: general concepts and characteristics of metabolic pathways.
Carbohydrate metabolism
(a) Pathways of glucose metabolism: glycolysis
(b) HMP shunt
(c) Gluconeogenesis
(d) Glycogenolysis, glycogenesis
(e) Galactose and fructose metabolism
(f) Glycogen storage disease
(g) Inborn errors of glucose metabolism
(h) Regulation of glucose metabolism.

Amino acid metabolism
(a) General reactions, transamination, its metabolic and diagnostic significance
(b) Disposal of amino acid nitrogen and detoxication of urea
(c) Metabolic fate of amino acid carbon skeleton
(d) Sulphur containing amino acids
(e) In born errors of branched chain and aromatic amino acids
(f) Important amino acid derivatives.

Lipid metabolism
(a) Biosynthesis and degradation of fatty acids, phospolipids and triacylglycerols
(b) Biosynthesis of cholesterol, chemistry and metabolism of lipoproteins.
(c) Hyperlipoproteinemias
(d) Lipid storage disease.
(e) Ketone bodies: their synthesis, utilization and conditions leading to ketoacidosis, prostaglandin.
TCA cycle and biological oxidation, prostanoids.

Regulation of the metabolic pathways
(a) Carbohydrate, lipid and amino acid metabolism
(b) Interlinks between these pathways.
(c) Organ interrelationships in metabolism,
(d) Blood glucose regulation, and its impairment in diabetes mellitus.
(e) Metabolic adaptation in the fed state, fasting and prolonged starvation.
(f) Metabolic derangements and adaptations in diabetes mellitus.

Food assimilation and nutrition
(a) Digestive enzymes, their action on dietary carbohydrates, fats and proteins.
(b) Absorption of glucose, amino acids and lipids.
(c) Gastric, pancreatic and intestinal function tests, liver function tests.
(d) Functions of dietary ingredients, the macro and micronutrients.
(e) Fat soluble and water soluble vitamins
(f) Malnutrition
(g) Iron metabolism and heme synthesis.

Hormones
(a) Molecular basis of hormonal action, signal transduction mechanisms.
(b) Chemistry, functions and mechanism of action of hormones of the pituitary, thyroid, parathyroid,
adrenals, panaceas, and gonads.
(c) Biosynthesis of steroid hormones their functions and mechanism of action.
(d) Pineal body

(e) Endorphins and encephalins,
(f) Calcium homeostasis.
(g) Hormonal interplay in the regulation of metabolism.

Molecular Biology
(a) Nucleic acids: DNA and RNA structure
(b) DNA Replication,
(c) DNA Transcription
(d) Post-transcriptional processing.
(e) Translation of genetic code
(f) Regulation of gene expression and protein synthesis inhibitors of protein synthesis.
(g) DNA repair mechanisms,
(h) Applied aspects of purine and pyrimidine metabolism
(i) Genetic Engineering: Recombinant DNA technology
(j) DNA and diagnostics
(k) DNA repair mechanisms and related disorders
(l) Telomers, telomerases
(m) Inhibitors of DNA replication, apoptosis

pH, Buffer, physiological buffer systems
(a) Regulation of blood pH, acidosis, alkalosis,
(b) Renal functions tests.

Immunology
(a) Reticuloendothelial system, components and functions of the innate and adaptive immunity.
(b) Role of T and B lymphocytes, antigen presentation
(c) Induction of immune response
(d) Cell mediated immune response
(e) Immunoglobulin structure and functions
(f) Humoral immune response
(g) Fate of antigen antibody complex,
(h) Complement system
(i) Generation of antibody diversity,
(j) Hypersensitivities
(k) Immunoregulation, autoimmunity, tolerance
(l) HLA, disease association & transplantation
(m) Immunological techniques, application in medicine (vaccines, immunotherapy, immunoassays and
immunodiagnostics).

Environmental biochemistry, cancer and cancer makers
(a) Xenbiotics, interaction with biomolecules, effects, metabolism, detoxication,
(b) Biochemical characteristics of cancer
(c) Environmental pollutants and carcinogenensis.

PRACTICALS
1. Laboratory Instrumentation.
2. Protein fractionation, denaturation, separation of proteins and amino acids.
3. Colour reactions of amino acids and proteins.
4. Estimation of blood analytes: glucose, total cholesterol and HDL cholesterol, uric acid, electrolytes,
urea.
5. Cerebrospinal fluid analyses.
6. Gastric juice analyses.
7. Urine analyses.
8. Amniotic fluid analyses.
9. Enzymes: amylase, lactate dehydrogenase and alkaline phosphatase
10. Liver function tests
11. Renal function tests.
12. Gel electrophoresis of DNA.
13. Immunodiffusion techniques, RIA and ELISA
14. Case-oriented discussions (enzymes, metabolites, function tests)
Biochemistry is taught in two semesters in the 1st year of the MBBS curriculum.
1st Semester : Aug-December
2nd Semester : Jan-June

TEACHING-LEARNING METHODOLOGY
1. Didatic lectures: three and a half hours/week of interactive classroom lectures to facilitate learning
of terminology, principles and concepts. Books and resource material are suggested to encourage
self- directed learning.
2. Tutorials; Two hours/week. Problem based small group discussions, questions-answer sessions,
revision and reinforcement of difficult concepts in tutorial hours. The purpose is to inculcate skills
of reasoning, meaningful approaches to learning and facilitate understanding of the subject.
3. Laboratory exercises: (Biochemistry practicals) three hours/week: a) to substantiate and clarify
theoretical concepts with experimental evidence b) to develop skills of performing basic biochemical
tests important in clinical investigations c) to develope familiarity with biochemical laboratory
instrumentations techniques.
(1) Practical bench work

(2) Demonstration
(3) Analyses and interpretation of data
(4) Discussions on the practicals with the help of clinical and scientific problems

TEXT-BOOKS RECOMMENDED
1. Biochemistry Ed. Lubert Stryer. W.H. Freeman and Company, New York.
2. Principles of Biochemistry. Ed. Lehinger, Nelson and Cox. CBS Publishers and distributors.
3. Harper”s Biochemistry, Ed. R.K. Murray, D.K. Granner, P.A. Mayes and V.W. Rodwell. Appleton
and Lange, Stamford, Connecticut.
4. Textbook of Biochemistry with Clinical Correlations. Ed. Thomas M. Devlin, Wiley-Liss Publishers.
5. Tietz Textbook of Clinical Chemistry. Ed. Burtis and Ashwood. W.B. Saunders Company.
6. Biochemistry. Ed. Donald Voet and Judith G. Voet. John Wiley & Sons, Inc.
7. Immunology Ed. 5th Richard A. Goldsby, Thomas J Kindt, Barbara A Osborne, Janis Kuby.
8. Immunology Ed. 6th Ivan Roitt, Jonathan Brostoff, David Male.

EXAMINATION & MARKS DISTRIBUTION
Semester examinations
1st mid Semester: held on 1st – 2nd week of October
1st end Semester: held on 1st – 2nd week of December
Second Semester: held on 1st – 2nd week of March.
Semester examinations are held both for the theory and practical courses.

1st professional Final (Summative) Examination: Students are assessed on the complete 1st year
syllabus in biochemistry theory and practicals.

Mark distribution
Semester examinations
Theory: total 75 (25 in each semester):
Practical: total 75 (25 in each semester)
Final Examination
Theory : Total 75
Practical : Total 75
Total marks (1st Prof. in Biochemistry)
Semester Examination 150
Final Examination 150
Total 300

Distribution of Topics
Paper I Cell structure, compartmentation, functions, biological membranes. Chemistry, functions
and metabolism of amino acids, carbohydrates and lipids, metabolic interrelationships, in
born errors of metabolism, nutrients and malnutrition, biological oxidation, hormones, vitamins
and coenzymes.

Paper II Protein structure and functions, hemoglobin, myoglobin, plasma proteins and iron metabolism,
enzymes and enzyme kinetics, nucleic acid biochemistry and molecular biology, immunology,
digestion and absorption, function Tests: G.I.T., kidney, and liver, regulation of acid base
balance, environmental biochemistry, cancer biochemistry.

Contact Details:
All India Institute of Medical Sciences
Ansari Nagar East,
Gautam Nagar,
New Delhi,
Delhi 110029 ‎
011 2658 8500 ‎
India